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Activation of protein kinase C by fatty acids and its dependency on Ca2+ and phospholipid
Y M Morimoto1, K Nobori, K Edashige
1Department of Medical Biology, Kochi Medical School, Japan.
Cell Structure and Function
|February 1, 1988
Abstract:
Ca2+- and phospholipid-dependent protein kinase (PKC) was activated by arachidonic and myristic acids. This activation by both fatty acids required the calcium ion. Acidic phospholipid was also required for the activation by myristic acid, while that by arachidonic acid was inhibited by phospholipid.