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Murine Model of Central Venous Stenosis using Aortocaval Fistula with an Outflow Stenosis
Published on: July 11, 2019
Endovascular Intervention for Central Venous Stenosis in Hemodialysis Patients: A Single-center Experience
Shobhana Nayak-Rao1, Bhanushree Ramanna2, K Subramanyam2
1Department of Nephrology, KS Hegde Medical Academy, Derlakatte, Karnataka, India.
Insights
Central venous stenosis (CVS) in hemodialysis patients can be successfully treated with percutaneous transluminal angioplasty and stenting. This intervention demonstrated good patency rates, highlighting its effectiveness in managing this condition.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Nephrology
Background:
- Central venous stenosis (CVS) significantly impacts hemodialysis access.
- Percutaneous transluminal angioplasty (PTA) with stenting is a primary treatment for CVS.
- Understanding procedural outcomes is crucial for patient management.
Observation:
- Ten hemodialysis patients with CVS underwent PTA with or without stenting.
- 90% of patients received PTA with primary stent insertion.
- Procedures were performed under sedation by interventional cardiologists.
Findings:
- Primary patency rates were 90% at 3 months, 70% at 24 months.
- No association found between patient demographics or dialysis vintage and patency.
- Successful treatment of CVS was achieved through angioplasty and stenting.
Implications:
- Percutaneous angioplasty and primary stenting are effective for treating central venous stenosis.
- Preventive strategies for CVS remain paramount despite successful interventions.
- Further research may explore long-term outcomes and prevention methods.
Abstract:
Central venous stenosis (CVS) refers to a significant stenosis of a large intrathoracic vein, such as the subclavian, brachiocephalic, or the superior vena cava (hemodialysis, HD). Percutaneous transluminal angioplasty (PTA) with or without stent placement has been the recommended as the preferred approach to CVS. A total of 10 consecutive HD patients with documented CVS over a 2-year time period from April 2017-April 2019 underwent percutaneous angioplasty and stent insertions under sedation. The procedure was performed by the interventional cardiologist in the institute. One patient underwent only PTA, whereas nine (90%) had PTA with primary stent insertion. Primary patency was 90% at 3 months, 80% at 6 months while at 12 months, it was 70% and remained at 70% at 24 months. We did not find any association between age, gender, diabetic status, dialysis vintage, or previous catheter infection with procedural patency. Central venous stenosis can be treated successfully with percutaneous angioplasty and primary stenting. Despite advances, prevention of CVS should be the primary approach.
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