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Updated: Nov 14, 2025

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
Sensitivity and specificity of chest computed tomography scan based on RT-PCR in COVID-19 diagnosis
Alireza Mirahmadizadeh1, Zahra Pourmontaseri2, Sima Afrashteh3
1Noncommunicable Diseases Research Center, Department of Epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran.
Purpose:
COVID-19 is a novel, severely contagious and progressive infection occurring worldwide. The diagnosis of the disease is based on real-time polymerase chain reaction (RT-PCR) and computed tomography (CT) scan, even though they are still controversial methods.
Material And Methods:
We studied 54 patients with suspected COVID-19 and the two mentioned methods were compared with each other.
Results:
Sensitivity and specificity of the abnormal chest CT scan, ground-glass opacity (GGO), consolidation opacity, and both of GGO and consolidation were also surveyed based on RT-PCR. The results showed that RT-PCR assay was negative in 23 (42.6%) patients and positive in 31 (57.4%) cases. Also, the patients with an abnormal chest CT scan comprised 37 (68.5%). The sensitivity and specificity of abnormal CT scan were 78.6% and 42.3%, respectively, based on the RT-PCR method.
Conclusions:
Other techniques alongside CT scan and RT-PCR are advocated for accuracy of the COVID-19 diagnosis.
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