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Updated: Nov 14, 2025

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
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Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia

Published on: December 19, 2020

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Involvement of the Mediastinal Subpleural Pulmonary Parenchyma on Chest CT in COVID-19 patients: A Case Series

Luigi Urciuoli1, Elvira Guerriero2, Lanfranco Musto1

  • 1Department of Radiology, G. Criscuoli Hospital, Sant'Angelo dei Lombardi, ASL Avellino, Avellino, Italy.

Journal of Radiology Case Reports
|March 12, 2021
PubMed

Insights

Chest CT scans reveal ground-glass opacities in the mediastinal subpleural parenchyma for COVID-19 patients. This finding, while atypical, should not decrease suspicion for SARS-CoV-2 infection.

Area of Science:

  • Radiology
  • Infectious Diseases
  • Pulmonology

Background:

  • Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, is a global pandemic.
  • While RT-PCR is the gold standard for diagnosis, CT scans are crucial for evaluation and follow-up.
  • Typical COVID-19 CT findings include peripheral, subpleural ground-glass opacities.

Observation:

  • This study reports on eight confirmed COVID-19 cases.
  • Unenhanced chest CT was performed for clinical evaluation and laboratory testing.
  • All patients exhibited ground-glass opacities in the mediastinal subpleural parenchyma.

Findings:

  • Chest CT scans in these COVID-19 cases demonstrated ground-glass opacities.
  • The opacities were located in the mediastinal subpleural parenchyma.
  • These findings, alongside typical COVID-19 CT features, were observed.

Implications:

  • Mediastinal subpleural parenchymal involvement on CT does not rule out COVID-19.
  • Radiologists should maintain a high index of suspicion for SARS-CoV-2.
  • Understanding varied CT presentations aids in accurate COVID-19 diagnosis and patient management.

Keywords:
COVID-19Coronavirus disease 2019GGOschest CTground-glass opacitieslung consolidationmediastinal pleura

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