Study of Anterior Commissure-Posterior Commissure Distance among Nepalese Cohort

Area of Science:

• Neuroimaging
• Anthropometry
• Neurosurgery

Background:

• The anterior commissure-posterior commissure (AC-PC) distance is a critical landmark in neuroimaging and stereotactic procedures.
• Variations in AC-PC distance across different ethnic groups are not well-documented.

Purpose of the Study:

• To determine the AC-PC distance in a Nepalese cohort.
• To compare the intercommissural distance of Nepalese individuals with other racial groups.

Main Methods:

• Magnetic resonance imaging (MRI) data from 47 patients (mean age 50 years) who underwent Deep Brain Stimulation (DBS) or lesioning were analyzed.
• Anterior commissure (AC) and posterior commissure (PC) marking was performed using Inomed Planning Software (IPS).

Main Results:

• The average AC-PC distance in the Nepalese cohort was 24.86 ± 2.08 mm (range: 16-30 mm).
• Males exhibited a longer AC-PC distance (25.38 mm) compared to females (24.02 mm).
• AC-PC distance showed a linear increase with age.

Conclusions:

• The Nepalese cohort's AC-PC distance is similar to Asian populations.
• AC-PC distance in Nepalese individuals is longer than in Hispanic populations and shorter than in Caucasian populations.