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The EQ-5D-5L Valuation Study in Egypt.

Sahar A Al Shabasy1, Maggie M Abbassi1, Aureliano Paolo Finch2

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This study developed the first EQ-5D-5L value set for Egypt, crucial for health economic evaluations. The new Egyptian EQ-5D-5L values will enhance pharmacoeconomic studies and health technology assessments within the country.

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Area of Science:

  • Health Economics
  • Psychometrics
  • Societal Preferences

Background:

  • No existing EQ-5D-5L value sets for Egypt hinder local pharmacoeconomic guidelines.
  • Previous Egyptian economic evaluations relied on external utility values.
  • A need exists for a country-specific EQ-5D-5L value set to improve study quality.

Purpose of the Study:

  • To develop the first Egyptian EQ-5D-5L value set.
  • To adhere to the international EuroQol standardized protocol (EQ-VT-2.1).
  • To provide a tool for accurate health state valuation in Egypt.

Main Methods:

  • Recruited adult Egyptian participants via multi-stratified quota sampling.
  • Employed composite time trade-off (cTTO) and discrete-choice experiments (DCEs) for data collection.
  • Utilized generalized least square, Tobit, heteroskedastic, logit, and hybrid models for data analysis, selecting the best fit.

Main Results:

  • Analyzed 974 valid interviews, excluding pilot and incomplete data.
  • Selected a heteroskedastic model (model 4) based on cTTO data for the value set.
  • Generated values from -0.93 (worst health) to 1 (full health), with mobility significantly impacting preferences.

Conclusions:

  • This is the inaugural EQ-5D-5L value set for Egypt and any Arabic-speaking nation.
  • The value set will serve as a scoring system for economic evaluations.
  • Implementation will enhance the quality of health technology assessment in Egypt.