Related Experiment Video
Updated: Nov 13, 2025
09:28
Engineering Molecular Recognition with Bio-mimetic Polymers on Single Walled Carbon Nanotubes
Published on: January 10, 2017
8.3K
Chiral Detection with Coordination Polymers.
1School of Chemistry, The University of Melbourne, Parkville, Victoria, 3010, Australia.
Chemistry, an Asian Journal
|March 12, 2021
Summary
Coordination polymers and metal-organic frameworks show promise as chiral sensors for enantioselective analysis. Recent advancements highlight their application in various chiral detection methods, expanding their utility in chemical sensing.
Area of Science:
- Materials Science
- Analytical Chemistry
- Supramolecular Chemistry
Background:
- Coordination polymers and metal-organic frameworks are recognized for chemical sensing.
- Their application as chiral probes is an emerging area of research.
- These porous materials offer unique host-guest properties for chiral recognition.
Purpose of the Study:
- To review recent advancements in coordination polymers as chiral sensors.
- To examine the enantioselective host-guest chemistry of these materials.
- To highlight the potential applications of coordination polymers in chiral analysis.
Main Methods:
- Literature review of recent works on coordination polymers as chiral sensors.
- Analysis of enantioselective host-guest interactions.
- Discussion of applications in chromatography, spectroscopy, and sensing.
Main Results:
- Coordination polymers have been successfully employed in various chiral analysis techniques.
- Enantioselective host-guest chemistry is a key feature enabling chiral sensing.
- Diverse applications in liquid/gas chromatography, CD spectroscopy, fluorescence, and NMR have emerged.
Conclusions:
- Coordination polymers are versatile platforms for developing advanced chiral sensors.
- Their porous structures facilitate enantioselective recognition and separation.
- Further exploration promises broader applications in chiral chemical sensing.
More Related Videos
10:52Line Shape Analysis of Dynamic NMR Spectra for Characterizing Coordination Sphere Rearrangements at a Chiral Rhenium Polyhydride Complex
Published on: July 27, 2022
3.1K
09:22Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
Published on: February 7, 2017
8.0K
Related Concept Videos
02:05Prochirality
4.5K
The concept of prochirality leads to the nomenclature of the individual faces of a molecule and plays a crucial role in the enantioselective reaction. It is a concept where two or more achiral molecules react to produce chiral products. A typical process is the reaction of an achiral ketone to generate a chiral alcohol. Here, the achiral reactant reacts with an achiral reducing agent, sodium borohydride, to generate an equimolar mixture of the chiral enantiomers of the product. For example, an...
4.5K
02:30Chirality at Nitrogen, Phosphorus, and Sulfur
6.5K
Chirality is most prevalent in carbon-based tetrahedral compounds, but this important facet of molecular symmetry extends to sp3-hybridized nitrogen, phosphorus and sulfur centers, including trivalent molecules with lone pairs. Here, the lone pair behaves as a functional group in addition to the other three substituents to form an analogous tetrahedral center that can be chiral.
A consequence of chirality is the need for enantiomeric resolution. While this is theoretically possible for all...
A consequence of chirality is the need for enantiomeric resolution. While this is theoretically possible for all...
6.5K
02:25Chirality
28.0K
Chirality is a term that describes the lack of mirror symmetry in an object. In other words, chiral objects cannot be superposed on their mirror images. For example, our feet are chiral, as the mirror image of the left foot, the right foot, cannot be superposed on the left foot.
Chiral objects exhibit a sense of handedness when they interact with another chiral object. For example, our left foot can only fit in the left shoe and not in the right shoe. Achiral objects — objects that have...
Chiral objects exhibit a sense of handedness when they interact with another chiral object. For example, our left foot can only fit in the left shoe and not in the right shoe. Achiral objects — objects that have...
28.0K
02:30Chirality in Nature
15.4K
Chirality is the most intriguing yet essential facet of nature, governing life’s biochemical processes and precision. It can be observed from a snail shell pattern in a macroscopic world to an amino acid, the minutest building block of life. Most of the snails around the world have right-coiled shells because of the intrinsic chirality in their genes. All the amino acids present in the human body exist in an enantiomerically pure state, except for glycine - the sole achiral amino acid.
15.4K
02:52Stereoisomerism
12.9K
Isomerism in Complexes
Isomers are different chemical species that have the same chemical formula.
Transition metal complexes often exist as geometric isomers, in which the same atoms are connected through the same types of bonds but with differences in their orientation in space. Coordination complexes with two different ligands in the cis and trans positions from a ligand of interest form isomers. For example, the octahedral [Co(NH3)4Cl2]+ ion has two isomers (Figure 1) In the cis...
Isomers are different chemical species that have the same chemical formula.
Transition metal complexes often exist as geometric isomers, in which the same atoms are connected through the same types of bonds but with differences in their orientation in space. Coordination complexes with two different ligands in the cis and trans positions from a ligand of interest form isomers. For example, the octahedral [Co(NH3)4Cl2]+ ion has two isomers (Figure 1) In the cis...
12.9K
02:25Molecules with Multiple Chiral Centers
14.3K
Molecules that possess multiple chiral centers can afford a large number of stereoisomers. For instance, while some molecules like 2-butanol have one chiral center, defined as a tetrahedral carbon atom with four different substituents attached, several molecules like butane-2,3-diol have multiple chiral centers. A simple formula to predict the number of stereoisomers possible for a molecule with n chiral centers is 2n. However, there can be a lower number where some of the stereoisomers are...
14.3K