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Defining abnormal cold sensitivity using the Cold Intolerance Symptom Severity questionnaire: a population study.

Albin Stjernbrandt1, Ingrid Liljelind1, Tohr Nilsson1

  • 1Section of Sustainable Health, Umeå University, Umeå, Sweden.

The Journal of Hand Surgery, European Volume
|March 12, 2021
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Summary
This summary is machine-generated.

This study establishes a clinical cut-off for abnormal cold sensitivity using the Cold Intolerance Symptom Severity (CISS) questionnaire. A CISS score above 50 indicates abnormal cold sensitivity in healthy adults.

Keywords:
HandSwedencold exposurehand-arm vibrationnerve injuryoccupational exposure

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Area of Science:

  • Orthopedics
  • Hand Surgery
  • Clinical Assessment

Background:

  • Cold sensitivity is a common, disabling issue after hand injuries.
  • The Cold Intolerance Symptom Severity (CISS) questionnaire assesses cold sensitivity.
  • Establishing a clinical threshold for abnormal scores is crucial for diagnosis.

Purpose of the Study:

  • To define a clinical cut-off for abnormal cold sensitivity using the CISS score in a healthy working-age population.
  • To examine the influence of age, gender, and prior injuries/diseases on CISS scores.

Main Methods:

  • A cohort of 1239 healthy working-age individuals in northern Sweden completed the CISS questionnaire.
  • Statistical analysis determined the 95th percentile for CISS scores in men and women.
  • The impact of demographic factors and medical history on scores was evaluated.

Main Results:

  • The 95th percentile CISS scores were 49.5 for men and 53.0 for women.
  • Factors like age, gender, and previous injuries had minimal clinical impact on CISS scores.
  • A CISS score exceeding 50 is supported as indicative of abnormal cold sensitivity.

Conclusions:

  • A CISS score above 50 serves as a reliable indicator of abnormal cold sensitivity.
  • The study provides a validated threshold for diagnosing cold sensitivity in clinical practice.
  • Demographic and historical factors do not significantly alter this clinical threshold.