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Updated: Nov 13, 2025

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Distraction Osteogenesis in Craniofacial Surgery: Past, Present, and Future
Petros Konofaos1, Robert D Wallace
1Department of Plastic Surgery, University of Tennessee Health Science Center, Memphis, TN.
Distraction osteogenesis (DO) effectively corrects craniofacial skeleton malformations by generating bone and soft tissue. This review covers 35 years of DO evolution in craniofacial surgery.
Area of Science:
- Craniofacial surgery
- Orthognathic surgery
- Regenerative medicine
Background:
- Distraction osteogenesis (DO) is a primary surgical treatment for craniofacial skeleton malformations.
- DO facilitates bone and soft tissue regeneration at the distraction site.
- It offers successful long-term outcomes for diverse craniofacial deformities.
Purpose of the Study:
- To review the evolution of distraction osteogenesis applications in craniofacial surgery.
- To provide an overview of the literature spanning the last 35 years.
- To highlight the advancements and established role of DO in treating craniofacial deformities.
Main Methods:
- Literature review of distraction osteogenesis in craniofacial surgery.
- Analysis of studies published over the past 35 years.
- Synthesis of information on DO techniques and outcomes.
Main Results:
- DO is a preferred method for correcting craniofacial deformities.
- DO promotes bone and soft tissue generation.
- Long-term outcomes are consistently successful.
Conclusions:
- Distraction osteogenesis has significantly advanced craniofacial surgery.
- Its ability to regenerate bone and soft tissue makes it a valuable technique.
- DO remains a cornerstone treatment for craniofacial malformations.
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