Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Parathyroid Glands00:59

The Parathyroid Glands

3.3K
The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
3.3K
Urinary Tract Calculi III: Medical Management01:30

Urinary Tract Calculi III: Medical Management

77
The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
77
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

170
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
170
Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

119
Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
119
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

195
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
195
Peptic Ulcer Disease V: Surgical Management and Nursing Care01:25

Peptic Ulcer Disease V: Surgical Management and Nursing Care

587
Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease
587

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Metabolic bone disorders: what the internist must not overlook].

Innere Medizin (Heidelberg, Germany)·2026
Same author

The use of denosumab in rare bone diseases in adults: a systematic review from the ECTS Rare Bone Disease Action Group.

The Journal of clinical endocrinology and metabolism·2026
Same author

Adjustment of total plasma calcium for albumin concentrations avoids overdiagnosis of hypocalcemia in geriatric patients.

Zeitschrift fur Gerontologie und Geriatrie·2026
Same author

The local inactivation of glucocorticoid as regulator for the development of glucocorticoid-induced osteoporosis.

PNAS nexus·2025
Same author

Health-related quality of life in a cohort of 1070 patients with hypoparathyroidism.

European journal of endocrinology·2025
Same author

Advances in the clinical management of parathyroid disorders: report from the 2024 workshop by the ESE educational program on parathyroid disorders.

European journal of endocrinology·2025

Related Experiment Video

Updated: Nov 13, 2025

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
07:12

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

4.2K

[Asymptomatic primary hyperparathyroidism : Operation or observation?]

Katja Gollisch1,2, Heide Siggelkow3,4

  • 1Klinik für Gastroenterologie, Gastrointestinale Onkologie und Endokrinologie, Universitätsmedizin Göttingen, Göttingen, Deutschland.

Der Internist
|March 12, 2021
PubMed
Summary
This summary is machine-generated.

Asymptomatic primary hyperparathyroidism (PHPT) requires specific diagnostic criteria, including elevated parathyroid hormone and specific calcium/phosphate levels. Treatment decisions for mild cases involve monitoring or surgery based on established indicators like hypercalcemia or osteoporosis.

Keywords:
Bone mineral densityFamilial hypocalciuric hypercalcemiaOsteoporosisParathyroidectomyVitamin D

More Related Videos

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
05:19

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

Published on: November 7, 2025

92
Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
03:57

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Published on: July 14, 2023

2.1K

Related Experiment Videos

Last Updated: Nov 13, 2025

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
07:12

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

4.2K
A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
05:19

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

Published on: November 7, 2025

92
Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
03:57

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Published on: July 14, 2023

2.1K

Area of Science:

  • Endocrinology
  • Nephrology
  • Bone Metabolism

Background:

  • Primary hyperparathyroidism (PHPT) often presents asymptomatically, detected incidentally through routine diagnostics.
  • Symptomatic PHPT typically necessitates surgical intervention, while management of asymptomatic cases remains a key clinical question.

Purpose of the Study:

  • To review current evidence-based recommendations for diagnosing and treating asymptomatic PHPT.
  • To provide guidance on when intervention is indicated for patients without overt symptoms.

Main Methods:

  • Diagnostic criteria for asymptomatic PHPT mirror those for symptomatic disease, focusing on parathyroid hormone and vitamin D levels.
  • Laboratory findings include hypercalcemia, hypophosphatemia, and hypercalciuria, with consideration for familial hypocalciuric hypercalcemia.
  • Imaging (ultrasound, radiography, CT) assesses for kidney complications; bone mineral density (BMD) measurements, including the distal radius, are crucial for detecting osteoporosis.

Main Results:

  • Surgical intervention for asymptomatic PHPT is indicated for significant hypercalcemia (>1.0 mg/dL above normal), hypercalciuria (>400 mg/day), renal insufficiency, osteoporosis, or age <50 years.
  • For patients not meeting surgical criteria and preferring non-operative management, annual laboratory monitoring and BMD assessment every 1-2 years are recommended.

Conclusions:

  • Diagnosis of asymptomatic PHPT relies on characteristic biochemical profiles and exclusion of other conditions.
  • Management strategies balance the risks and benefits of parathyroidectomy versus conservative monitoring based on specific clinical and biochemical markers.