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The minimally invasive interbody selection algorithm for spinal deformity.
Praveen V Mummaneni1, Ibrahim Hussain2, Christopher I Shaffrey3
11Department of Neurological Surgery, University of California, San Francisco, California.
Journal of Neurosurgery. Spine
|March 12, 2021
Summary
Minimally invasive surgery (MIS) for spinal deformity now has a decision-making framework. The minimally invasive interbody selection algorithm (MIISA) guides surgeons on choosing approaches like ALIF, ACR, LLIF, and TLIF for better outcomes.
Area of Science:
- Spine surgery
- Orthopedic surgery
- Minimally invasive spinal techniques
Background:
- Minimally invasive surgery (MIS) is crucial for spinal deformity correction, decompression, and arthrodesis.
- Current selection criteria for specific interbody approaches in MIS for spinal deformity are lacking.
- A structured decision-making framework is needed for rational surgical planning.
Purpose of the Study:
- To develop and validate the minimally invasive interbody selection algorithm (MIISA) for MIS spinal deformity surgery.
- To provide a rational framework for selecting among anterior lumbar interbody fusion (ALIF), anterior column release (ACR), lateral lumbar interbody fusion (LLIF), and transforaminal lumbar interbody fusion (TLIF).
Main Methods:
- Retrospective analysis of circumferential MIS (cMIS) for adult spinal deformity (ASD) over 5 years.
- Surgeon preferences and segmental lordosis outcomes were evaluated at each lumbar level.
- A Delphi session with minimally invasive deformity surgeons informed algorithm creation.
- Comparison of preoperative and 2-year postoperative radiographic and clinical outcomes.
Main Results:
- The MIISA was developed with substantial agreement among 11 surgeons performing 100 cMISs.
- Surgeons preferred LLIF for L1-4, with ACR used for greater lordosis needs.
- At L4-5, preferences were LLIF, TLIF, and ALIF; at L5-S1, ALIF and TLIF were preferred.
- ALIF and ACR demonstrated significant lordosis restoration, while LLIF alone did not.
Conclusions:
- The MIISA offers consistent guidance for MIS spinal deformity surgery.
- The algorithm prioritizes lateral approaches for upper lumbar levels and reserves ACR for significant lordosis correction.
- Specific interbody choices at L4-5 and L5-S1 depend on desired lordosis restoration.

