Functionalized chitosan as a novel support for stabilizing palladium in Suzuki reactions

Area of Science:

• Biopolymer Chemistry
• Catalysis
• Organic Synthesis

Background:

• Chitosan is a biodegradable polysaccharide with facile modification capabilities.
• Developing efficient and stable catalysts is crucial for sustainable organic transformations.

Purpose of the Study:

• To develop a novel stabilizer agent from chitosan for palladium immobilization.
• To evaluate the catalytic activity, stability, and reusability of the resulting palladium complex in Suzuki reactions.

Main Methods:

• Synthesis of chitosan-derived stabilizer agent (OCMCS-SB) and its palladium complex (OCMCS-SB-Pd(II)).
• Characterization using 13C CP-MAS NMR, FT-IR, TGA, XRD, XPS, SEM, TEM, and ICP-OES.
• Evaluation of catalytic performance in Suzuki reactions and reusability tests.

Main Results:

• The OCMCS-SB-Pd(II) complex exhibited excellent reactivity (up to 99%) and stability in Suzuki reactions.
• The catalyst demonstrated high reusability over five consecutive cycles with no significant loss of activity.
• A trifunctional complex structure was proposed based on interactions with chitosan functional groups.

Conclusions:

• The bio-based OCMCS-SB-Pd(II) system offers a promising and sustainable approach for utilizing chitosan in organic transformations.
• The developed palladium complex shows excellent catalytic efficiency and recyclability, suitable for eco-friendly Suzuki reactions.