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Multi-photon Imaging of Tumor Cell Invasion in an Orthotopic Mouse Model of Oral Squamous Cell Carcinoma
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Published on: July 25, 2011

An unusual presentation of metastatic squamous carcinoma of tongue

L D Stone1, M L Harries

  • 1Academic Surgical Unit, Royal Marsden Hospital, London, U.K.

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
|June 1, 1988
PubMed

Abstract:

Distant metastases from head and neck carcinoma are becoming more common, with lung, bone and liver being the most frequent sites. We present an unusual case of a metastasis from a tongue primary presenting with severe abdominal pain and pseudo large bowel obstruction.

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Metastasis02:30

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...

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