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Related Experiment Video

Updated: Nov 13, 2025

Chondrogenic Pellet Formation from Cord Blood-derived Induced Pluripotent Stem Cells

Chondrogenic Pellet Formation from Cord Blood-derived Induced Pluripotent Stem Cells

Published on: June 19, 2017

Korea National Stem Cell Bank.

Jung-Hyun Kim¹, Hye-Yeong Jo¹, Hye-Yeong Ha¹

¹Korea National Stem Cell Bank, South Korea; Division of Intractable Diseases Research, Department of Chronic Diseases Convergence Research, Korea National Institute of Health, Osong Health Technology Administration Complex 202, South Korea.

Stem Cell Research

|March 14, 2021

Summary

The Korea National Stem Cell Bank distributes quality-controlled pluripotent stem cell lines, including human embryonic stem cell and induced pluripotent stem cell lines. They ensure cell line quality through rigorous testing and provide genetic data for public research.

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Last Updated: Nov 13, 2025

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Published on: June 19, 2017

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Area of Science:

Biotechnology
Regenerative Medicine
Genomics

Background:

The Korea National Stem Cell Bank has been actively banking pluripotent stem cell (PSC) lines since 2012.
Cell lines are developed for distribution, ensuring quality control and ethical sourcing.

Purpose of the Study:

To report on the status of distributed cell lines as of 2020.
To highlight the availability of Good Manufacturing Practices (GMP)-compliant induced pluripotent stem cell (iPSC) lines for regenerative medicine.
To detail the quality control measures and genetic data availability for banked cell lines.

Main Methods:

Distribution of 4 research-grade human embryonic stem cell (hESC) lines and 19 induced pluripotent stem cell (iPSC) lines from 69 deposited lines.
Deposit of GMP-compliant homozygous iPSC lines with HLA haplotypes covering 51% of the Korean population.
Performance of eighteen distinct quality control tests assessing identity, sterility, consistency, stability, and safety.

Main Results:

As of 2020, a significant number of PSC lines have been distributed for research purposes.
Availability of specialized iPSC lines suitable for regenerative medicine applications.
Comprehensive quality testing has been conducted on all distributed cell lines.

Conclusions:

The Korea National Stem Cell Bank provides a valuable resource of quality-controlled and ethically sourced PSC lines.
Genetic stability data (SNPchip, WES, Methyl-seq, RNA-seq) are being collected and made publicly accessible.
The bank supports research and regenerative medicine by offering diverse and well-characterized stem cell lines.