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Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
Published on: October 24, 2018
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Extracorporeal membrane oxygenation in intensive care unit
Éva Zöllei1,2, Gábor Bari3, Ivett Blaskovics4,5
11 Szegedi Tudományegyetem, Általános Orvostudományi Kar, Aneszteziológiai és Intenzív Terápiás Intézet, Szeged.
Orvosi Hetilap
|March 14, 2021
Summary
Extracorporeal membrane oxygenation (ECMO) is a vital treatment for severe respiratory and circulatory failure. This study demonstrates that implementing ECMO programs in Hungarian centers yields survival rates comparable to international benchmarks.
Area of Science:
- Cardiovascular and Respiratory Medicine
- Intensive Care Medicine
- Extracorporeal Life Support
Background:
- Extracorporeal membrane oxygenation (ECMO) is increasingly utilized globally for refractory respiratory and circulatory failure.
- The establishment of an ECMO program requires careful planning and execution, integrating physiological principles with clinical application.
- Veno-venous (VV) configuration is a primary mode for respiratory support, while veno-arterial (VA) configuration supports both respiratory and circulatory functions.
Purpose of the Study:
- To review the physiological basis of extracorporeal membrane oxygenation (ECMO), particularly the veno-venous configuration.
- To present the initial outcomes of patients treated with ECMO at our institution.
- To assess the feasibility and effectiveness of establishing an ECMO program in a tertiary care setting.
Main Methods:
- Systematic review of the existing literature on extracorporeal membrane oxygenation.
- Retrospective analysis of data from 14 patients treated with ECMO since 2016.
- Evaluation of patient demographics, indications for ECMO, configuration used, duration of support, and patient outcomes.
Main Results:
- Fourteen patients (8 male, mean age 51 ± 15 years) received ECMO support, primarily for refractory hypoxemic respiratory failure (9 cases).
- Respiratory support was provided in 11 patients (13 VV, 1 VA) for a mean of 14 ± 6 days; circulatory support in 3 patients for a mean of 5 ± 4 days.
- Nine patients were discharged in good functional condition; 5 died during intensive care, and 3 died later during hospitalization, indicating feasibility and comparable survival rates to international data.
Conclusions:
- The implementation of an extracorporeal membrane oxygenation program is achievable in Hungarian tertiary centers.
- Adherence to international recommendations and training standards allows for survival outcomes similar to those reported globally.
- ECMO is a viable and effective treatment modality for severe respiratory and circulatory failure, contributing to improved patient outcomes.
Keywords:
extracorporalis membránoxigenizációextracorporeal membrane oxygenationintensive therapyintenzív kezeléslégzési elégtelenségrespiratory insufficiencyMore Related Videos
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