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NEXUS Arch: A Multicenter Study Evaluating the Initial Experience With a Novel Aortic Arch Stent Graft System
David Planer1, Gabby Elbaz-Greener1, Nicola Mangialardi2,3
1Heart Institute, Hadassah - Hebrew University Medical Center, Jerusalem, Israel.
Annals of Surgery
|March 14, 2021
Summary
The NEXUS Aortic Arch Stent Graft System shows high success in endovascular aortic arch repair, with excellent 1-year safety and performance for complex aortic pathologies.
Area of Science:
- Cardiovascular Surgery
- Endovascular Repair
- Aortic Arch Pathology
Background:
- The aortic arch presents significant challenges for both open and endovascular repair.
- Transcatheter aortic arch repair offers a less invasive alternative to reduce surgical risks.
Purpose of the Study:
- To evaluate the initial clinical outcomes of the NEXUS Aortic Arch Stent Graft System.
- To assess its safety and performance in treating aortic arch pathologies.
Main Methods:
- Transcatheter aortic arch repair using a novel single-branch, 2-stent graft system.
- Implantation involved a through-and-through guidewire technique with proximal landing in Zone 0.
- Debranching procedures were performed in all patients.
Main Results:
- 100% procedural success in 28 patients treated for aortic arch aneurysms and dissections.
- 1-year mortality was 10.7%, with no device or aneurysm-related deaths.
- Low rates of stroke (3.6% at 30 days, 7.1% at 1 year) and unplanned reinterventions (10.7%).
Conclusions:
- The NEXUS system demonstrates high success rates for endovascular aortic arch repair.
- It offers excellent 1-year safety and performance in managing complex aortic arch conditions.
