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Severe hypercalcaemia and acute renal failure in an infant with subcutaneous fat necrosis
Tülay İnce Becerir1, Ayça Altincik1, Bayram Özhan1
1Divisions of Nephrology and Endocrinology, Department of Paediatrics, Pamukkale University Faculty of Medicine, Denizli, Turkey.
Abstract:
Subcutaneous fat necrosis (SFN) in the newborn is a form of panniculitis which presents with erythematous nodules and indurated plaques. Severe life-threatening hypercalcaemia can occur as a late complication. A 2-month-old girl presented with severe hypercalcaemia and acute renal injury as a complication of SFN. She was admitted to hospital with the chief complaint of failure to thrive. She had a history of therapeutic hypothermia. After successful treatment of the hypercalcaemia with bisphosphonates, the acute renal injury recovered spontaneously. In neonates with SFN, acute renal injury is a rare complication of hypercalcaemia. Timely prevention of the complications of hypercalcaemia in SFN is essential.
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