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Aptasensors for mycotoxin detection: A review.

Xhensila Shkembi1, Marketa Svobodova1, Vasso Skouridou1

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Analytical Biochemistry
|March 15, 2021
PubMed
Summary

Aptasensors offer a rapid and cost-effective solution for detecting multiple mycotoxins in food and feed. This review details aptamer selection and sensor strategies for improved safety and quality control.

Keywords:
Aflatoxin B1, B2Fumonisin B1OchratoxinPatulinT-2 toxinZearalenone

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Area of Science:

  • Food Science
  • Analytical Chemistry
  • Biotechnology

Background:

  • Mycotoxins, toxic fungal compounds, pose significant risks to the food and feed supply chain, impacting health and economies.
  • Multiple mycotoxin contaminations are frequently detected in feed samples, necessitating efficient detection methods.
  • Current testing methods require improvement in terms of speed, cost-effectiveness, and simplicity for accurate screening.

Purpose of the Study:

  • To review aptamers selected against mycotoxins.
  • To describe the integration of these aptamers into optical and electrochemical aptasensors.
  • To outline strategies, advantages, and disadvantages of various aptasensor approaches for mycotoxin detection.

Main Methods:

  • Aptamer selection methodologies for mycotoxins.
  • Design and fabrication of optical and electrochemical aptasensors.
  • Evaluation of different materials and immobilization techniques for sensor development.

Main Results:

  • Various aptamers have been successfully selected for mycotoxin detection.
  • Aptasensors demonstrate potential for sensitive and selective mycotoxin screening.
  • Different sensor designs and materials offer distinct advantages and limitations.

Conclusions:

  • Aptasensors represent a promising tool for rapid, cost-effective, and accurate mycotoxin detection.
  • Further research into materials and immobilization is crucial for optimizing aptasensor performance.
  • Enhanced detection capabilities will improve food and feed safety and quality control.