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Published on: November 28, 2019
Innate and adaptive immune cells in Tumor microenvironment
1Department of Oral Medicine and Oral Oncology, Krishnadevaraya College of Dental Sciences, Bengaluru - 562157, India.
Abstract:
Innate and adaptive immune cells recruited to the tumor microenvironment by chemokines following noxious stimuli such as physical or chemical or infectious agents. Innate and adaptive immune cells release inflammatory mediators such as cytokines, chemokines, growth factors, proteolytic enzymes, activate transcription factors (NF-KB, STAT3,HIF-1a) results in tumor initiation, promotion, and progression. This article highlights about the role of innate and adaptive immune cells in tumor microenvironment.
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