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The Assessment of the Platelet Function During the Acute Phase of ST-segment Elevation Myocardial Infarction in

Shinnosuke Kikuchi1, Kiyoshi Hibi1, Kouichi Tamura2

  • 1Division of Cardiology, Yokohama City University Medical Center, Japan.

Internal Medicine (Tokyo, Japan)
|March 15, 2021
PubMed

We encountered a case of ST-segment elevation myocardial infarction (STEMI) as the first clinical manifestation of essential thrombocythemia (ET). Platelet function tests revealed high thrombogenicity during primary percutaneous coronary intervention compared with general cardiovascular patients, whereas the platelet function two weeks after admission was effectively suppressed by dual antiplatelet therapy. The patient, who lacked cytoreduction, suffered from recurrent STEMI because of poor compliance with antiplatelet drugs. The risk of acute coronary occlusion may be high during the acute phase of STEMI in ET patients because of high thrombogenicity. Insufficient antiplatelet therapy and no cytoreduction are also risk factors for recurrent coronary events.

Keywords:
ST-segment elevation myocardial infarctioncase reportessential thrombocythemiaplatelet function

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