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Thyroid Angiosarcoma-Rare Case or Hard to Find
Konstantinos Sapalidis1, Nikos Kefes1, Konstantinos Romanidis2
13rd Surgery Department, Medical School of Health Sciences, Aristotle University of Thessaloniki, "AHEPA" University Hospital, Thessaloniki, Greece.
Current Health Sciences Journal
|March 15, 2021
Summary
Thyroid angiosarcoma, a rare and aggressive cancer, presents unique diagnostic challenges. This case highlights the importance of prompt surgical intervention for this vascular malignancy, despite its poor prognosis.
Area of Science:
- Oncology
- Pathology
- Vascular Neoplasms
Background:
- Thyroid angiosarcoma is a rare malignancy originating from thyroid gland endothelial cells.
- It exhibits a higher incidence in specific mountainous regions and is associated with a poor prognosis.
Observation:
- A 76-year-old male presented with respiratory distress, hoarseness, fatigue, and dysphagia.
- Physical examination revealed neck purpura and a palpable thyroid nodule; imaging confirmed thyroid enlargement.
- Fine-needle aspiration cytology (FNAC) suggested malignancy, leading to total thyroidectomy.
Findings:
- Postoperative cytopathology confirmed primary thyroid angiosarcoma.
- The patient experienced disease progression and succumbed to the illness six months post-surgery.
Implications:
- Angiosarcomas are aggressive, highly hemorrhagic vascular tumors requiring specialized diagnosis.
- Surgical resection is the primary treatment, though adjuvant therapies remain debated.
- Metastasis and surrounding tissue infiltration are critical negative prognostic indicators for thyroid angiosarcoma.

