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Published on: May 21, 2015
Maternal and Neonatal Outcomes of COVID-19 in Pregnancy: A Single-Centre Observational Study
Vinita Singh1, Anisha Choudhary1, Mamta R Datta1
1Obstetrics and Gynecology, Tata Main Hospital, Jamshedpur, IND.
Insights
COVID-19 in pregnancy often presents as asymptomatic or mild illness. While associated with increased preterm births and neonatal ICU admissions, intrauterine and neonatal deaths are low, with minimal vertical transmission of SARS-CoV-2.
Area of Science:
- Obstetrics and Gynecology
- Infectious Diseases
- Neonatology
Background:
- The COVID-19 pandemic presents significant healthcare challenges, particularly for pregnant individuals.
- Understanding the clinical course and outcomes of COVID-19 in pregnancy is crucial for effective management.
Purpose of the Study:
- To evaluate the clinical presentation of COVID-19 in pregnant women.
- To assess the impact of COVID-19 on maternal and neonatal outcomes during pregnancy.
Main Methods:
- Retrospective observational study at a tertiary care hospital in Eastern India.
- Included 132 pregnant women positive for COVID-19 (May-November 2020).
- Data collected on clinical presentation, comorbidities, delivery methods, and neonatal outcomes.
Main Results:
- Most cases were asymptomatic (65.15%) or mild (34.09%).
- High rates of preterm delivery (28.69%) and C-section (63.93%) were observed.
- Neonatal intensive care unit admission rate was 33.06%, with 1.65% of neonates testing positive for SARS-CoV-2 within 24 hours.
Conclusions:
- COVID-19 in pregnancy typically manifests as asymptomatic or mild disease.
- Associated with elevated rates of preterm birth and neonatal ICU admissions.
- Low rates of intrauterine/neonatal death and minimal vertical transmission of SARS-CoV-2.
Background:
The current coronavirus disease 2019 (COVID-19) pandemic is one of the most challenging healthcare crises faced globally. Adequate information and understanding of the clinical presentation and impact of the disease on maternal and neonatal outcomes is the key to successfully manage a pregnancy with COVID-19.
Objective:
The purpose of the present study was to evaluate the clinical presentation of COVID-19 in pregnancy, its course during pregnancy and its effects on maternal and neonatal outcomes.
Study Design And Setting:
This study was a retrospective observational study conducted at Tata Main Hospital, Jamshedpur, a tertiary care hospital in Eastern India. Population and study period: All COVID-19-positive (by reverse transcription polymerase chain reaction or rapid antigen test) pregnant women admitted to the hospital from 15th May 2020 to 15th November 2020. Results: A total of 132 COVID-19-positive pregnant women were included in the study. Eighty-six women (65.15%) were asymptomatic, 45 women (34.09%) had mild symptoms and one woman had severe disease. Major co-morbidities seen were hypertensive disorders (pre-eclampsia, gestational hypertension and chronic hypertension) in 18 (13.64%) and diabetes (gestational diabetes, diabetes mellitus type 2) in 14women (10.60%). The rate of preterm delivery was 28.69% (n=35). Caesarean section was done for 78 women (63.93%) and 44 (36.07%) delivered vaginally. Average birth weight reported was 2.59 kilograms. Forty babies (33.06%) were admitted to the neonatal intensive care unit. Two babies (1.65%) tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) within 24 hours of delivery. Conclusion: COVID-19 in pregnancy commonly presents as an asymptomatic or mild disease. It is associated with high rates of preterm births and neonatal admissions to the intensive care unit. Intrauterine and neonatal death rates remain low. Vertical transmission is possible; however, the incidence is low, and the majority of these neonates are asymptomatic.
