Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Elastin is Responsible for Tissue Elasticity01:12

Elastin is Responsible for Tissue Elasticity

2.8K
Elastic fiber contains the protein elastin along with lesser amounts of other proteins and glycoproteins. The main property of elastin is that it will return to its original shape after being stretched or compressed. Elastic fibers are prominent in elastic tissues found in skin and the elastic ligaments of the vertebral column.
Ligaments and tendons are made of dense regular connective tissue, but in ligaments not all fibers are parallel. Dense regular elastic tissue contains elastin fibers and...
2.8K
Assembly of Cytoskeletal Filaments01:18

Assembly of Cytoskeletal Filaments

24.9K
Cytoskeletal filaments are polymeric forms of smaller protein subunits. However, individual cytoskeletal filaments may easily disassemble or associate with other similar filaments to form rigid structures. Microfilaments, made of actin monomers, rely on actin-binding proteins to form bundles and create networks of individual actin filaments. Microtubules rely on microtubule-associated proteins (MAPs) to form sturdy cylindrical structures. However, the proteins involved in forming complex...
24.9K
Cytoskeletal Accessory Proteins01:13

Cytoskeletal Accessory Proteins

3.6K
The cytoskeleton is an essential cell component that plays several structural and functional roles. However, the filaments that make up the cytoskeleton cannot function independently and depend on the accessory or ancillary proteins to effectively carry out their function. Accessory proteins associate with cytoskeletal filaments and their monomers, aiding filament formation and function. They also help in the cross-communication among cytoskeletal filaments. Cytoskeletal accessory proteins are...
3.6K
Protein Complex Assembly02:41

Protein Complex Assembly

14.9K
Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
Many viruses self-assemble into a fully functional unit using the infected host cell to...
14.9K
Protein Complex Assembly02:41

Protein Complex Assembly

2.3K
2.3K
Formation of Higher-order Actin Filaments01:11

Formation of Higher-order Actin Filaments

3.3K
The polymerization of G-actin monomers into filamentous F-actin is a multi-step process. Once the F-actins are formed, they can bundle together in different arrangements to form higher-order networks and regulate cellular functions. Common examples include the formation of lamellipodia and filopodia at the cell's leading edge by actin reorganization in a migrating cell. The microvilli on the brush border epithelial cells are also formed through the F-actin network.
The high-order actin...
3.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spontaneous spinal CSF leaks: a rare variant exome sequencing study and functional analysis.

The Lancet. Neurology·2026
Same author

Structural and biophysical analysis of the four CHRD domains of human chordin reveals a novel binding site for glycosaminoglycans.

The Journal of biological chemistry·2026
Same author

Grafts in tendon repair.

Materials today. Bio·2026
Same author

Functions of prolyl hydroxylation in elastin.

The Journal of biological chemistry·2026
Same author

Human pluripotent stem cell model of multiple epiphyseal dysplasia with MATN3 mutation identifies altered matrix organisation and upregulation of the cholesterol biosynthesis pathway.

Osteoarthritis and cartilage·2026
Same author

An avidity-driven mechanism of extracellular BMP regulation by Twisted gastrulation.

Development (Cambridge, England)·2026

Related Experiment Video

Updated: Nov 13, 2025

Directed Assembly of Elastin-like Proteins into defined Supramolecular Structures and Cargo Encapsulation In Vitro
10:01

Directed Assembly of Elastin-like Proteins into defined Supramolecular Structures and Cargo Encapsulation In Vitro

Published on: April 8, 2020

6.1K

Tropoelastin and Elastin Assembly.

Jazmin Ozsvar1,2, Chengeng Yang3, Stuart A Cain4

  • 1Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.

Frontiers in Bioengineering and Biotechnology
|March 15, 2021
PubMed
Summary
This summary is machine-generated.

Elastic fibers provide essential stretch to tissues. Recent research clarifies how tropoelastin

Keywords:
assemblycomputational modelingelastic fiberselastintropoelastin

More Related Videos

Design and Construction of Artificial Extracellular Matrix aECM Proteins from Escherichia coli for Skin Tissue Engineering
10:30

Design and Construction of Artificial Extracellular Matrix aECM Proteins from Escherichia coli for Skin Tissue Engineering

Published on: June 11, 2015

9.1K
ECM Protein Nanofibers and Nanostructures Engineered Using Surface-initiated Assembly
16:33

ECM Protein Nanofibers and Nanostructures Engineered Using Surface-initiated Assembly

Published on: April 17, 2014

12.7K

Related Experiment Videos

Last Updated: Nov 13, 2025

Directed Assembly of Elastin-like Proteins into defined Supramolecular Structures and Cargo Encapsulation In Vitro
10:01

Directed Assembly of Elastin-like Proteins into defined Supramolecular Structures and Cargo Encapsulation In Vitro

Published on: April 8, 2020

6.1K
Design and Construction of Artificial Extracellular Matrix aECM Proteins from Escherichia coli for Skin Tissue Engineering
10:30

Design and Construction of Artificial Extracellular Matrix aECM Proteins from Escherichia coli for Skin Tissue Engineering

Published on: June 11, 2015

9.1K
ECM Protein Nanofibers and Nanostructures Engineered Using Surface-initiated Assembly
16:33

ECM Protein Nanofibers and Nanostructures Engineered Using Surface-initiated Assembly

Published on: April 17, 2014

12.7K

Area of Science:

  • Biochemistry
  • Cell Biology
  • Extracellular Matrix Research

Background:

  • Elastic fibers, crucial for tissue resilience, are primarily composed of elastin.
  • Elastin is assembled from its monomer, tropoelastin.
  • Studying elastin and tropoelastin assembly is challenging due to their intrinsic properties.

Purpose of the Study:

  • To review recent advancements in understanding elastin assembly.
  • To explore the relationship between tropoelastin structure and function in fiber formation.

Main Methods:

  • Literature review of recent developments in elastin research.
  • Analysis of studies focusing on tropoelastin structure-function relationships.

Main Results:

  • Recent studies have shed light on previously unclear aspects of elastin assembly.
  • The review highlights how tropoelastin's structural characteristics influence its assembly into elastic fibers.

Conclusions:

  • Understanding tropoelastin's structure-function relationship is key to deciphering elastic fiber formation.
  • Continued research in this area is vital for advancing knowledge of connective tissues.