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Advances in emergent biological recognition elements and bioelectronics for diagnosing COVID-19
Praopim Limsakul1,2, Krit Charupanit3, Chochanon Moonla4
1Division of Physical Science, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla, 90112 Thailand.
Emergent Materials
|March 15, 2021
Summary
New biosensors offer rapid and reliable alternatives for detecting SARS-CoV-2, the virus causing COVID-19. These advancements in biodiagnosis are crucial for early detection and controlling the pandemic.
Area of Science:
- Biomaterials Science
- Infectious Disease Diagnostics
- Nanotechnology
Background:
- Coronaviruses, including SARS-CoV-2, present significant public health challenges.
- Current COVID-19 diagnosis relies heavily on RT-PCR, necessitating faster and simpler alternatives.
- Biosensors offer a promising avenue for rapid and selective virus detection.
Purpose of the Study:
- To review biorecognition materials for SARS-CoV-2 detection.
- To summarize recent advances in biosensors and bioelectronics for COVID-19 diagnosis.
- To provide an outlook on the future of rapid coronavirus detection technologies.
Main Methods:
- Literature review of scholarly articles (primarily 2020-2021) on biosensors for COVID-19.
- Focus on biorecognition elements (antibodies, antibody-like molecules) targeting SARS-CoV-2 biomarkers.
- Inclusion of recent developments in bioelectronic sensing for coronaviruses.
Main Results:
- Biorecognition material design is critical for high sensitivity and selectivity in virus detection.
- Various antibodies and antibody-like molecules have been developed for SARS-CoV-2 recognition.
- Recent advancements show progress in bioelectronic devices for coronavirus sensing.
Conclusions:
- Biosensor-based approaches provide effective alternatives for rapid COVID-19 diagnosis.
- Optimizing biorecognition layers enhances biosensing performance for sensitive and selective virus detection.
- Continued development in biosensors and bioelectronics is vital for pandemic preparedness and early disease intervention.
