Short pulsed microwave ablation: computer modeling and ex vivo experiments
Related Experiment Video
Updated: Jun 18, 2026
Thermal Ablation for the Treatment of Abdominal Tumors
Published on: March 7, 2011
Aleksandar Radosevic1, Diego Prieto2, Fernando Burdío3
1Department of Radiology, Hospital del Mar, Universitat Pompeu Fabra, Barcelona, Spain.
Purpose:
To study the differences between continuous and short-pulse mode microwave ablation (MWA).
Methods:
We built a computational model for MWA including a 200 mm long and 14 G antenna from Amica-Gen and solved an electromagnetic-thermal coupled problem using COMSOL Multiphysics. We compared the coagulation zone (CZ) sizes created with pulsed and continuous modes under ex vivo and in vivo conditions. The model was used to compare long vs. short pulses, and 1000 W high-powered short pulses. Ex vivo experiments were conducted to validate the model.
Results:
The computational models predicted the axial diameter of the CZ with an error of 2-3% and overestimated the transverse diameter by 9-11%. For short pulses, the ex vivo computer modeling results showed a trend toward larger CZ when duty cycles decreases. In general, short pulsed mode yielded higher CZ diameters and volumes than continuous mode, but the differences were not significant (<5%), as in terms of CZ sphericity. The same trends were observed in the simulations mimicking in vivo conditions. Both CZ diameter and sphericity were similar with short and long pulses. Short 1000 W pulses produced smaller sphericity and similar CZ sizes under in vivo and ex vivo conditions.
Conclusions:
The characteristics of the CZ created by continuous and pulsed MWA show no significant differences from ex vivo experiments and computer simulations. The proposed idea of enlarging coagulation zones and improving their sphericity in pulsed mode was not evident in this study.
