Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

249
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
249
Bias01:22

Bias

6.6K
Bias refers to any tendency that prevents a question from being considered unprejudiced. In research, bias occurs when one outcome or answer is selected or encouraged over others in sampling or testing. Bias can occur during any research phase, including study design, data collection, analysis, and publication.
In statistics, a sampling bias is created when a sample is collected from a population, and some members of the population are not as likely to be chosen as others (remember, each member...
6.6K
Bias in Epidemiological Studies01:29

Bias in Epidemiological Studies

948
Biases can arise at various stages of research, from study design and data collection to analysis and interpretation. Recognizing and addressing these biases is essential to ensure the validity and reliability of epidemiological findings.Broadly speaking, biases in epidemiology fall into three main categories: selection bias, information bias, and confounding. A more detailed description of possible biases is:  
948
Blind Procedures02:07

Blind Procedures

12.5K
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
12.5K
Ethical Issues01:27

Ethical Issues

1.6K
Nurses are essential in patient care, upholding the ethical principles of their profession and effectively navigating ethical dilemmas. Neglecting ethical issues can lead to inadequate patient care, compromised therapeutic relationships, and moral distress among healthcare workers.
Ethical Concerns in Healthcare:
1.6K
Blinding01:11

Blinding

3.7K
Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.
3.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect of Age on Short-Term Readmissions Following Transcatheter Edge-to-Edge Repair of the Mitral Valve.

Structural heart : the journal of the Heart Team·2026
Same author

Disparities through the looking glass.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2025
Same author

Corrigendum to Racial disparities across multiple stages of the deceased organ donation process.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2024
Same author

Racial disparities across multiple stages of the deceased organ donation process.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2024
Same author

Impact of socioeconomic deprivation on evaluation for heart transplantation at an urban academic medical center.

Clinical transplantation·2022
Same author

Psychological distress, coping behaviors, and preferences for support among New York healthcare workers during the COVID-19 pandemic.

General hospital psychiatry·2020

Related Experiment Video

Updated: Nov 12, 2025

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo
09:19

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo

Published on: February 6, 2015

8.9K

Are the current evaluation tools for advanced therapies biased?

Raymond C Givens1

  • 1Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York, USA.

Current Opinion in Cardiology
|March 15, 2021
PubMed
Summary

Racial bias may affect access to advanced heart failure (HF) therapies. Addressing systemic inequities in healthcare requires multi-level commitments to improve access and standardize care.

More Related Videos

Home-Based Monitor for Gait and Activity Analysis
07:24

Home-Based Monitor for Gait and Activity Analysis

Published on: August 8, 2019

7.0K
In Vitro Tumor Cell Rechallenge For Predictive Evaluation of Chimeric Antigen Receptor T Cell Antitumor Function
08:04

In Vitro Tumor Cell Rechallenge For Predictive Evaluation of Chimeric Antigen Receptor T Cell Antitumor Function

Published on: February 27, 2019

12.2K

Related Experiment Videos

Last Updated: Nov 12, 2025

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo
09:19

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo

Published on: February 6, 2015

8.9K
Home-Based Monitor for Gait and Activity Analysis
07:24

Home-Based Monitor for Gait and Activity Analysis

Published on: August 8, 2019

7.0K
In Vitro Tumor Cell Rechallenge For Predictive Evaluation of Chimeric Antigen Receptor T Cell Antitumor Function
08:04

In Vitro Tumor Cell Rechallenge For Predictive Evaluation of Chimeric Antigen Receptor T Cell Antitumor Function

Published on: February 27, 2019

12.2K

Area of Science:

  • Cardiology
  • Health Equity
  • Health Services Research

Background:

  • Racial disparities in chronic disease outcomes, including heart failure (HF), persist despite awareness.
  • Recent events underscore the impact of systemic racism on health outcomes.
  • The influence of racial bias on access to advanced HF therapies remains largely unexamined.

Purpose of the Study:

  • To investigate whether racial bias influences patient access to advanced heart failure therapies.
  • To identify specific points in the evaluation process vulnerable to bias.

Main Methods:

  • Review of existing literature on racial bias in healthcare settings.
  • Analysis of medical and psychosocial factors in advanced HF therapy evaluations.

Main Results:

  • Evidence suggests racial bias impacts HF providers' consideration of patients for advanced therapies.
  • Specific elements within the patient evaluation process are susceptible to bias.

Conclusions:

  • Reducing disparities in advanced therapy access necessitates multi-level interventions.
  • Key strategies include improving healthcare access, standardizing clinical operations, researching patient success factors, and increasing provider diversity.
  • Significant investment and disruptive change are needed, comparable to efforts against COVID-19.