Metal Hypersensitivity in Joint Arthroplasty
Related Experiment Video
Updated: Nov 12, 2025

Potentiodynamic Corrosion Testing
Published on: September 4, 2016
Johannes Michiel van der Merwe1
1From the Adult Reconstruction Orthopaedic Department, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Abstract:
Metal hypersensitivity in joint arthroplasty is a very controversial topic with limited evidence. With increasing numbers of joint replacements being done annually, a clear understanding of the pathogenesis, clinical picture, preimplant screening, postimplant workup, and treatment plan is crucial. This review article looked at all the available evidence regarding metal hypersensitivity and summarized the key findings. An algorithm was also proposed for preimplant screening, postimplant workup, and management.
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