Related Experiment Video
Updated: Nov 12, 2025

The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia
Published on: November 30, 2016
[A cachectic man with a severe vitamin deficiency].
S Franssen1,2, M A Beek1, S M Lagarde1
1Erasmus MC, afd. Heelkunde, Rotterdam.
A patient with vitamin E deficiency and malnutrition developed a complete bowel obstruction. This case highlights the severe gastrointestinal complications associated with nutritional deficiencies.
Area of Science:
- Gastroenterology
- Neurology
- Nutritional Science
Background:
- Severe malnutrition and vitamin E deficiency can lead to significant health complications.
- Peripheral neuropathies are a known consequence of vitamin E deficiency.
- Gastrointestinal dysfunction may be associated with severe malnutrition.
Observation:
- A 57-year-old male presented with vomiting and abdominal tenderness.
- Clinical suspicion for ileus and small bowel obstruction was noted.
- Exploratory laparotomy revealed a non-peristaltic, brown-colored bowel.
Findings:
- The intraoperative finding of a completely immobile, discolored bowel suggests a severe form of intestinal dysfunction.
- This presentation is consistent with a catastrophic outcome of prolonged malnutrition and vitamin E deficiency.
- The absence of peristalsis indicates a loss of normal bowel motility.
Implications:
- This case underscores the critical role of adequate nutrition in maintaining gastrointestinal integrity and function.
- Vitamin E repletion and nutritional support are crucial in managing patients with deficiencies.
- Further research may explore the direct mechanisms by which vitamin E deficiency impacts bowel motility.
More Related Videos
05:53Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
04:01Author Spotlight: Advanced Integrated Model for Sepsis-Induced Myopathy and Single-Cell Metabolic Analysis
Published on: June 14, 2024
Related Concept Videos
Vitamins
Overview of Protein Metabolism
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Chronic Kidney Disease III: Interprofessional Care
Role of Vitamins in Maintaining Bone Health
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Anorexia Nervosa
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...