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Related Experiment Videos

Primary hyperparathyroidism and angina pectoris.

G A Slavich1, F Antonucci, E Sponza

  • 1Institute of Cardiology, Regional Hospital, Udine, Italy.

International Journal of Cardiology
|May 1, 1988
PubMed
Summary
This summary is machine-generated.

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A patient with angina pectoris and normal coronary arteries was found to have hypercalcemia due to a parathyroid adenoma. Surgical removal of the adenoma resolved both hypercalcemia and angina symptoms.

Area of Science:

  • Cardiology
  • Endocrinology
  • Nephrology

Background:

  • Angina pectoris is chest pain caused by reduced blood flow to the heart.
  • Normal coronary arteriography indicates no significant blockages in the heart's arteries.
  • Hypercalcemia, high blood calcium levels, can have various underlying causes.

Observation:

  • A 50-year-old female presented with angina pectoris and a positive exercise stress test, despite normal coronary arteriography.
  • Initial treatment with nifedipine provided symptomatic relief for her angina.
  • Further laboratory investigations revealed hypercalcemia, prompting a search for its cause.

Findings:

  • The hypercalcemia was diagnosed as resulting from a parathyroid adenoma.
  • Surgical excision of the parathyroid adenoma was performed.

Related Experiment Videos

  • Post-surgery, the patient's serum calcium levels normalized.
  • Implications:

    • This case highlights a potential link between parathyroid adenoma, hypercalcemia, and angina pectoris.
    • Resolution of hypercalcemia through adenoma removal led to the complete cessation of angina symptoms.
    • The findings suggest that parathyroid adenoma should be considered in the differential diagnosis of angina with normal coronary arteries.