Related Experiment Video
Updated: Nov 12, 2025

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
Published on: April 12, 2021
Text message reminders for adolescents with poorly controlled type 1 diabetes: A randomized controlled trial
Nour Ibrahim1,2, Jean-Marc Treluyer1,3, Nelly Briand1
1Clinical Research Unit, Paris Descartes, Assistance Publique-Hôpitaux de Paris, Necker University Hospital, Paris, France.
Text message reminders (SMS) show a trend toward improving glycemic control in adolescents with type 1 diabetes. While not statistically significant in all analyses, SMS interventions may support behavior change for better diabetes management.
Area of Science:
- Endocrinology
- Pediatrics
- Digital Health
Background:
- Adolescents with type 1 diabetes often struggle with treatment adherence, increasing complication risks.
- Glycemic control is a critical factor in managing type 1 diabetes and preventing long-term health issues.
Purpose of the Study:
- To evaluate the impact of Short Messaging Service (SMS) reminders on glycemic control in adolescents with type 1 diabetes.
- To assess the feasibility and patient satisfaction of using SMS for diabetes management support.
Main Methods:
- A randomized controlled trial involving adolescents aged 12-21 years with type 1 diabetes and elevated HbA1c levels (≥ 69 mmol/mol).
- The intervention group received daily SMS reminders for insulin injections, while the control group received standard care.
- Data were analyzed using intent-to-treat and per-protocol approaches over a 6-month period.
Main Results:
- The SMS group showed a trend towards lower median HbA1c levels (73 mmol/mol) compared to the control group (83 mmol/mol) in intent-to-treat analysis (P=0.03).
- A significant proportion of patients with baseline HbA1c ≥ 80 mmol/mol achieved at least a 1% decrease in HbA1c in the SMS arm (60%) versus the control arm (30.6%) (P=0.03).
- Patients in the SMS arm reported high satisfaction with the intervention.
Conclusions:
- SMS interventions show a promising trend for improving glycemic control in adolescents with poorly controlled type 1 diabetes.
- Further research is needed to address methodological limitations and confirm the efficacy of SMS-based support for behavior change in this population.
More Related Videos
Related Concept Videos
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Insulin: Dosing Regimen and Adverse Effects
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Diabetes Mellitus: Type 2 and Gestational
Carbohydrate Metabolism
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Insulin Formulations: Types and Delivery
Short-acting insulins are divided into...

