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Does menstruation-related headache occur exclusively in women with migraine?

Alanny Gabrielly Diógenes Campelo1, Danilo Andrade Lima1, Gabriel Rios Carneiro Britto1

  • 1Federal University of Delta of Parnaíba, Avenida São Sebastião, 2819, Fátima, Parnaíba, 64001-020, Brazil.

Acta Neurologica Belgica
|March 15, 2021
PubMed

To determine the relation between headache and menstruation in women with migraine and the use of estrogen by these women. This was a prospective, cross-sectional, observational study with group comparison, using non-random sample and convenience. We interviewed 79 women diagnosed with migraine or tension-type headache (TTH), according to the ICHD-3, regarding the relation between headache and menstruation. Of the 79 women with headache, 60 (76%) had migraine and 19 (24%) had episodic TTH. The most frequent subtype of migraine was without aura (54/60, 90%). The age ranged from 18 to 42 years, with an average of 22.6 ± 4.1 years. Migraine affected women aged 22.4 ± 3.6 years, whereas in TTH, the age was 23.0 ± 5.4 years. Menstruation-related headache occurred in 41.9% of women with migraine and in only 6.3% of those with TTH. These differences were significant (χ2 = 5.2; p = 0.022). Of the five women diagnosed with migraine with aura, two used estrogen. Menstruation-related headache predominates in women with migraine and often women with migraine with aura use estrogen.

Keywords:
EstrogenMenstruationMigraineTriggering factors

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