Related Experiment Video
Updated: Nov 12, 2025

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
Published on: February 23, 2014
Risk factors for childhood pneumonia: a case-control study in a high prevalence area in Indonesia
Vivi Ninda Sutriana1, Mei Neni Sitaresmi2, Abdul Wahab3
1Master in Public Health Sciences Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada, Yogyakarta, Indonesia.
Insights
Exclusive breastfeeding and complete immunizations are key to preventing childhood pneumonia. Risk factors include poor feeding, lack of vaccines, indoor air pollution, low birth weight, and severe malnutrition.
Area of Science:
- Pediatrics
- Public Health
- Infectious Diseases
Background:
- Acute respiratory infections (ARIs), particularly pneumonia, are a leading cause of infant mortality globally.
- Pneumonia is the second-leading cause of death in infants and toddlers in Indonesia.
- Exclusive breastfeeding and routine immunizations are protective measures against pneumonia.
Purpose of the Study:
- To identify risk factors associated with childhood pneumonia in high-prevalence Indonesian regions.
- To inform public health strategies for pneumonia prevention in Indonesia.
Main Methods:
- A case-control study was conducted from March to April 2019.
- 176 infants and toddlers (10-59 months) were enrolled from a community health center.
- Pneumonia cases were diagnosed clinically per WHO guidelines; controls had no pneumonia.
Main Results:
- Key risk factors for pneumonia included: no or nonexclusive breastfeeding (OR 7.95), incomplete immunizations (OR 4.47), indoor air pollution (OR 7.12), low birth weight (OR 3.27), and severe wasting (OR 2.77).
- Maternal education, child's age, and sex were not significant risk factors.
- Nutritional status (height-for-age z-score) did not emerge as a risk factor.
Conclusions:
- Nonexclusive breastfeeding, incomplete immunizations, indoor air pollution, low birth weight history, and severe malnutrition are significant risk factors for childhood pneumonia.
- Breastfeeding emerged as the most dominant protective factor.
- Child's sex was found to modify the association between exclusive breastfeeding and pneumonia incidence.
Background:
Acute respiratory infections (ARIs), especially pneumonia, remain a major cause of infant mortality worldwide. In Indonesia, pneumonia is the second most common cause of infant and toddler deaths. Exclusive breastfeeding and basic immunization can protect infants and children from contracting pneumonia.
Purpose:
Our goal was to assess the risk factors for childhood pneumonia in regions with a high prevalence of pneumonia in Indonesia.
Methods:
This case-control study was conducted between March and April 2019. A total of 176 infants and toddlers aged 10-59 months were enrolled and selected from among patients who visited the community health center. Cases of pneumonia were diagnosed clinically based on the World Health Organization guidelines, and the control was nonpneumonia.
Results:
The risk factors for the diagnosis of pneumonia included no or nonexclusive breastfeeding (odds ratio [OR], 7.95; 95% confidence interval [CI], 3.52-17.94), incomplete basic immunizations (OR, 4.47; 95% CI, 2.22-8.99), indoor air pollution (OR, 7.12; 95% CI, 3.03-16.70), low birth weight (OR, 3.27; 95% CI, 1.19-8.92), and a high degree of wasting (OR, 2.77; 95% CI, 1.06-7.17). Other variables such as nutritional status (height-for-age z score), age, sex, and educational status of the mother were not risk factors for pneumonia.
Conclusion:
No or nonexclusive breastfeeding, incomplete basic immunizations, indoor air pollution, a history of low birth weight, and severe malnutrition were risk factors for childhood pneumonia. Breastfeeding was the dominant factor, while sex modified the relationship between exclusive breastfeeding and the incidence of pneumonia.
Related Concept Videos
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia III: Complications and Assessment
Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
Pneumonia II: Pathophysiology
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Cycle: Exhalation

