Related Experiment Video

Updated: Nov 12, 2025

Author Spotlight: Advancing Cancer Associated Thrombosis Research in Rodent Models
04:40

Author Spotlight: Advancing Cancer Associated Thrombosis Research in Rodent Models

Published on: January 5, 2024

2.8K

Risk for deep venous thrombosis in pediatric cancer patients undergoing surgery

Hannah R Spiegl1, Jeremie H Estepp2, Chen Li3

  • 1Department of Surgery, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, United States.

Journal of Pediatric Surgery
|March 16, 2021
PubMed

Insights

Surgery in pediatric cancer patients showed a low incidence of deep venous thrombosis (DVT), suggesting routine prophylaxis is not needed. This study analyzed DVT risk in young cancer patients undergoing major operations.

Area of Science:

  • Pediatric Oncology
  • Vascular Surgery
  • Thrombosis Research

Background:

  • Cancer is a known risk factor for deep venous thrombosis (DVT).
  • The incidence of DVT in pediatric cancer patients undergoing surgery requires further investigation.
  • Understanding perioperative DVT risk is crucial for optimizing patient care.

Purpose of the Study:

  • To determine the incidence of deep venous thrombosis (DVT) in pediatric cancer patients after major oncologic surgery.
  • To identify specific surgical procedures associated with a higher risk of DVT.
  • To evaluate the necessity of routine DVT prophylaxis in this patient population.

Main Methods:

  • Retrospective review of pediatric cancer patients who underwent major oncologic operations between 2000 and 2018.
  • Exclusion of catheter-associated DVTs from the analysis.
  • Identification of symptomatic DVTs occurring within 30 days post-operatively.

Main Results:

  • A total of 3031 major oncologic operations were performed.
  • Fourteen symptomatic DVTs were identified, resulting in an overall incidence of 0.46%.
  • Procedures linked to DVT included mass biopsy, pulmonary wedge resection, and inguinal lymph node excision.

Conclusions:

  • Surgery does not appear to pose a significant risk for DVT in pediatric cancer patients.
  • The low incidence of perioperative DVT suggests routine pharmacologic prophylaxis may not be warranted.
  • Further research could explore risk stratification for DVT in this vulnerable group.
Abstract

Keywords:
DVT prophylaxisDeep vein thrombosisPediatric oncologySurgeryVenous thromboembolism

More Related Videos

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis06:45

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis

Published on: February 10, 2023

14.9K
A Patient-Derived Xenograft Model for Venous Malformation06:51

A Patient-Derived Xenograft Model for Venous Malformation

Published on: June 15, 2020

5.5K

Related Concept Videos

Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
111
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
103
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
79
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
109
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
121
Varicose Veins I: Introduction01:26

Varicose Veins I: Introduction

Varicose veins, or varicosities, are abnormally dilated and twisted superficial veins caused by venous valve incompetence. This condition commonly affects the lower extremities, especially the saphenous veins, due to the higher pressure from prolonged standing and walking. However, varicosities can also occur in other areas, such as the esophagus, vulva, spermatic cords, and anorectal region.Etiology and typesPrimary varicose veins, often idiopathic, are more common in women due to inherent...
71