Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Radiation: Applications01:17

Radiation: Applications

1.4K
The average temperature of Earth is the subject of much current discussion. Earth is in radiative contact with both the Sun and dark space; it receives almost all its energy from the radiation of the Sun and reflects some of it into outer space. Dark space is very cold, about 3 K, so Earth radiates energy into it. For instance, heat transfer occurs from soil and grasses, the rate of which can be so rapid that frost can occur on clear summer evenings, even in warm latitudes.
The average...
1.4K
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

3.5K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.5K
Cancer Therapies02:49

Cancer Therapies

8.9K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
8.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Retrieval-Augmented Generation in Oncology: Promises, Pitfalls, and Early Applications.

AI in precision oncology·2026
Same author

American Brachytherapy Society Working Group Report on cancer surveillance, sexual health, and pelvic toxicity management in gynecologic malignancies.

Brachytherapy·2026
Same author

Overcoming Cancer Disparities Globally: Contributions of Norman Coleman.

Disaster medicine and public health preparedness·2026
Same author

Risk factors for hypospadias: a prospective single-center study from Ghana.

World journal of urology·2025
Same author

Local management of second breast cancer event after primary breast conserving therapy: The patient's perspective.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2025
Same author

The Society for Women in Radiation Oncology 5 Years Later: Connection, Representation, and Inclusivity Matter.

Practical radiation oncology·2025

Related Experiment Video

Updated: Nov 12, 2025

Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

18.4K

The Case for Brachytherapy: Why It Deserves a Renaissance.

Vonetta M Williams1, Jenna M Kahn2, Nikhil G Thaker3

  • 1Department of Radiation Oncology, University of Washington, Seattle, Washington.

Advances in Radiation Oncology
|March 16, 2021
PubMed
Summary

Brachytherapy offers shorter radiation courses for cancer treatment, maintaining outcomes while improving accessibility and reducing resource use. This hypofractionated radiation therapy is poised for a resurgence in oncology.

More Related Videos

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

20.7K
Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

16.0K

Related Experiment Videos

Last Updated: Nov 12, 2025

Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

18.4K
Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

20.7K
Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

16.0K

Area of Science:

  • Oncology
  • Radiation Oncology
  • Medical Physics

Background:

  • The COVID-19 pandemic has shifted oncologic treatment priorities towards preserving outcomes, enhancing accessibility, and optimizing resource utilization.
  • Brachytherapy, a key component in treating prostate and gynecologic cancers, enables hypofractionated radiation delivery, shortening treatment duration.
  • Despite evidence of equivalent or superior outcomes, brachytherapy usage declined in the early 2000s.

Purpose of the Study:

  • To highlight the potential for brachytherapy to meet the growing demand for shorter radiation courses in cancer care.
  • To emphasize brachytherapy's role in delivering hypofractionated, conformal radiation therapy.
  • To discuss the factors contributing to a potential resurgence of brachytherapy in clinical practice.

Main Methods:

  • Review of existing studies on brachytherapy outcomes and usage trends.
  • Analysis of brachytherapy's technical capabilities in delivering hypofractionated radiation.
  • Examination of the impact of recent global health events and healthcare policy on treatment modality selection.

Main Results:

  • Brachytherapy facilitates hypofractionated radiation, aligning with the need for shorter treatment times.
  • Emerging data suggest a reversal of the previous decline in brachytherapy utilization.
  • Hypofractionated radiation, exemplified by brachytherapy, is likely to become a standard of care across various cancer sites.

Conclusions:

  • Brachytherapy is well-positioned for a renaissance due to its efficacy, ability to deliver hypofractionated radiation, and extensive supporting data.
  • The shift towards shorter radiation courses and evolving reimbursement policies favor brachytherapy.
  • Brachytherapy represents an advanced form of conformal radiation therapy with proven long-term outcomes.