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Updated: Nov 12, 2025

Genome-Wide Analysis of DNA Methylation in Gastrointestinal Cancer
Published on: September 18, 2020
Gastric Melanoma of Unknown Primary
Fabio Cortellini1, Giovanni Marasco2, Matteo Renzulli3
1Azienda Ospedaliero-Universitaria di Bologna, Bologna; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy. . fabio.cortellini@studio.unibo.it.
Abstract:
We describe a case of a patient with anemia referring to our Digestive Endoscopy Unit. Upper GI endoscopy revealed a polypoid lesion with an ulcerated central depression. Histopathological examination of the biopsy specimen taken during endoscopy revealed a gastric metastatic melanoma. The dermatologic inspection failed in finding the primary melanoma. The importance of endoscopic examination in the diagnostic process of metastatic patients with unknown primaries is highlited by this case.

