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Related Concept Videos

Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

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Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
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Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

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Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
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Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

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Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
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Regulation of Stroke Volume01:27

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The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
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Related Experiment Video

Updated: Nov 12, 2025

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
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Evolving ischemic stroke subtypes in 15 years: A hospital-based observational study.

Bonaventure Ip1, Lisa Au1, Anne Chan1

  • 1Division of Neurology, Department of Medicine and Therapeutics, 26451The Chinese University of Hong Kong, Hong Kong.

International Journal of Stroke : Official Journal of the International Stroke Society
|March 16, 2021
PubMed
Summary

Ischemic stroke incidence declined due to better atherosclerosis management, but cardioembolic stroke cases rose. Enhanced AF screening and anticoagulation are crucial for future stroke prevention.

Keywords:
Secondary preventionatrial fibrillationepidemiologyincidenceintracranial stenosisprimary prevention

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Area of Science:

  • Neurology
  • Epidemiology
  • Public Health

Background:

  • Time trends in ischemic stroke subtypes are vital for effective, etiology-based prevention and treatment strategies.
  • Understanding these trends informs healthcare resource allocation.
  • This study examines the evolution of ischemic stroke subtypes over a 15-year period.

Purpose of the Study:

  • To analyze the changing incidence and recurrence rates of major ischemic stroke subtypes.
  • To identify trends in stroke etiologies from 2004 to 2018.
  • To provide insights for targeted stroke prevention efforts.

Main Methods:

  • Analysis of consecutive first-ever transient ischemic attack or ischemic stroke patients (n=6940) from 2004-2018.
  • Calculation of age-standardized incidences for major stroke subtypes.
  • Assessment of two-year recurrence rates and medication use (statin, dual antiplatelet therapy, anticoagulation).

Main Results:

  • Overall ischemic stroke incidence decreased significantly (187.0 to 127.4 per 100,000), driven by reductions in large artery disease and small vessel disease.
  • Cardioembolic stroke incidence remained stable, but its proportion increased (20.4% to 29.3%).
  • Two-year recurrence rates for atherothrombotic stroke (19.3% to 5.1%) and AF-related stroke (18.9% to 6%) significantly decreased, correlating with increased medication use.

Conclusions:

  • Etiology-based risk factor control likely reduced atherosclerosis-related strokes.
  • Increased AF-related strokes necessitate enhanced arrhythmia screening and anticoagulation.
  • Implementing comparable preventive strategies could significantly reduce the stroke burden.