Related Experiment Video
Updated: Nov 12, 2025

Techniques of Sleeve Gastrectomy and Modified Roux-en-Y Gastric Bypass in Mice
Published on: March 20, 2017
Metabolic and Bariatric Surgery in Adolescents
Christopher G Chalklin1, Elizabeth G Ryan Harper1, Andrew J Beamish2,3,4
1Cardiff and Vale University Health Board, Cardiff, UK.
Purpose Of Review:
The prevalence of obesity is increasing in all age groups. Following its success in adults, and with limited success using conservative therapies, metabolic and bariatric surgery (MBS) is increasingly being utilized in adolescents. This review highlights the current evidence and guidelines supporting its use.
Recent Findings:
Safety and efficacy mirror results seen in adults. The most recent evidence, as outcomes enter the long term, suggests that comorbidity resolution, including diabetes and hypertension, can even outperform that of adults. Mental health problems persist despite good weight loss. Overall, the positive early weight and comorbidity outcomes are well sustained into the long term. There is a growing need to prevent and treat adolescent obesity. Current evidence supports the use of MBS in adolescents. Ongoing and future studies will provide 10-year outcomes and assist in the refinement of multimodal pathways incorporating MBS for the treatment of severe childhood obesity.
Related Concept Videos
Obesity
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution
Bulimia Nervosa
Pharmacokinetics in Pediatric Patients: Drug Metabolism
Binge Eating Disorders
Signs of Puberty

