Related Experiment Video
Updated: Nov 12, 2025

Knee Arthrocentesis in Adults
Published on: February 25, 2022
Average narcotic usage in a group of TKA patients following a modern TKA protocol
Timothy G Costales1, Patrick H Greenwell1, Danielle M Chapman2
1University of Maryland Medical Center, 110 South Paca Street 6(th) Floor Suite 300, Baltimore, MD 21201, United States.
Introduction:
The optimal dosing of post-operative total knee arthroplasty (TKA) narcotics is unclear. We report on the average narcotic usage in a group of patients treated with an identical multimodal pain protocol following TKA.
Materials And Methods:
49 patients undergoing TKA participated in the survey. Patients with pre-op narcotic use, recent prior total joint arthroplasty or study refusal were excluded. All patients received a spinal anesthetic. No pre-surgery narcotics were given. All received an identical local infiltrative anesthetic combination along with a multimodal pain protocol. Patients were placed into an identical rapid rehab program. Narcotic usage during hospitalization was recorded in morphine equivalent doses (MED). Patients were given a journal to record their daily narcotic utilization.
Results:
Pre-operative pain scores of the excluded groups had slightly higher but clinically insignificant differences compared to the study group. In the hospital, POD1 study group daily MED averaged 28 (range 0-110). POD2 had an average of 33.6 and POD 3 daily usages averaged 28.6 (range 0-100). By the end of week two, the average daily use was 19.2 and 24% patients were off all narcotics. By the end of week four, the average daily usage was 7.5 and 63% of patients were off all narcotics. By 8 weeks, there were no patients still taking narcotics. KSS averaged 76.9 (range 51-97) at the 6 week visit, and 94.2 at the 3-month visit (range 72-100).
Summary:
This study documents the average needs of an average TKA patient treated with modern pain protocols. The majority of these patients were off narcotics by week four.
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