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Early versus late tube feeding initiation after PEG tube placement: Does time to feeding matter?
S Wesley1, N Samuels1, K Williams1
1Morehouse School of Medicine, Department of Surgery, 720 Westview Drive SW, Atlanta, GA 30310, USA.
Insights
Early tube feeding after percutaneous endoscopic gastrostomy (PEG) placement is safe and effective in trauma patients. This study found no significant difference in feeding intolerance or complications between early and late tube feeding initiation.
Area of Science:
- Gastroenterology
- Trauma Surgery
- Clinical Nutrition
Background:
- Timing of enteral nutrition initiation post-percutaneous endoscopic gastrostomy (PEG) placement varies.
- Optimal timing for initiating tube feeds after PEG placement remains debated.
Purpose of the Study:
- To compare outcomes of early tube feed (ETF) initiation (<24 hours) versus late tube feed (LTF) initiation (>24 hours) after PEG placement in trauma patients.
Main Methods:
- Retrospective review of 295 trauma patients who underwent PEG placement between January 2014 and December 2018.
- Primary outcome: feeding intolerance; Secondary outcomes: post-operative complications.
- Statistical analysis using standard methods (Pearson's Chi-squared, Fisher's exact, Mann Whitney-U tests).
Main Results:
- No significant difference in feeding intolerance at 12, 24, or 48 hours between ETF and LTF groups.
- No significant difference in specific intolerance symptoms (nausea, vomiting, abdominal tenderness, high gastric residuals, aspiration) between groups.
- No significant difference in post-operative complications between ETF and LTF groups.
Conclusions:
- Early tube feeding initiation after PEG placement is safe and comparable to late initiation in adult trauma patients.
- Further prospective research is needed to definitively establish the optimal timing for initiating tube feeds post-PEG placement.
Background:
Variation exists in the timing of tube feed initiation after percutaneous endoscopic gastrostomy (PEG) tube placement. The aim of our study was to review outcomes of early tube feed (ETF) versus late tube feed (LTF) initiation after PEG tube placement.
Methods:
We performed a retrospective review of all trauma patients who underwent PEG tube placement from 1/2014 to 12/2018. ETF was defined as initiation < 24 h and LTF > 24 h after placement. The primary outcome measure was feeding intolerance and secondary outcomes included post-operative complications. All statistical analyses were performed using standard statistical methods (e.g. Pearson's Chi-squared, Fisher's exact and Mann Whitney-U tests).
Results:
There were 295 patients (164 ETF and 131 LTF) that received a PEG tube at our level 1 trauma center. There was no difference with feeding intolerance at 12 h (5% vs. 4%; p = 0.88), 24 h (1% vs. 2%; p = 1.00), and 48 h (4% vs. 4%; p = 1.00). There was no difference when comparing intolerance symptoms such as nausea and vomiting (1% vs. 2%; p = 0.79), abdominal tenderness (2% vs. 3%; p = 0.76), high gastric residuals (2% vs. 2%; p = 1.00) and aspiration (0% vs. 2%; p = 0.39). There was no difference when comparing post-operative complications (4% vs. 8%; p = 0.21).
Conclusions:
Early tube feeding after PEG placement is safe and equivalent to late tube feeding in the adult trauma population. Future prospective studies are warranted to establish the optimal timing for initiation of tube feeds after PEG tube placement.
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