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Related Experiment Videos

Pathological changes in the brain in equine grass sickness.

J A Wright1, N P Hodson

  • 1Department of Pathology, Royal Veterinary College, London, U.K.

Journal of Comparative Pathology
|February 1, 1988
PubMed
Summary
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Neuropathological lesions in cranial nerves were observed in horses with grass sickness and one with laminitis. These findings suggest that such lesions are not specific to grass sickness in equine neurology.

Area of Science:

  • Equine neurology
  • Veterinary pathology
  • Neuropathology

Background:

  • Grass sickness is a devastating equine disease with poorly understood etiology.
  • Lesions in cranial nuclei have been anecdotally reported in grass sickness cases.

Purpose of the Study:

  • To investigate the presence and nature of lesions in cranial nuclei in horses diagnosed with grass sickness.
  • To compare these findings with those in horses with other conditions and controls.

Main Methods:

  • Histopathological examination of cranial nuclei from 11 horses with grass sickness.
  • Comparative analysis with one horse with laminitis and control horses.

Main Results:

  • Widespread lesions were identified in the cranial nuclei of all 11 horses with grass sickness.

Related Experiment Videos

  • Similar neuropathological changes were observed in one horse with laminitis.
  • No such lesions were found in control animals.
  • Conclusions:

    • The described lesions in cranial nuclei appear to be non-specific.
    • These findings indicate that similar neuropathological changes can occur in conditions other than grass sickness, warranting careful interpretation in equine neurological diagnoses.