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Related Concept Videos

Types of Fever01:25

Types of Fever

780
Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:
780
Patterns of Fever01:26

Patterns of Fever

3.3K
Before understanding the types and patterns of fever, it is essential to know its phases.
3.3K
Increased Body Temperature01:25

Increased Body Temperature

6.1K
A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
6.1K
Methods of reducing fever01:22

Methods of reducing fever

960
The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
960
Acute Pharyngitis01:30

Acute Pharyngitis

2.5K
Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
2.5K
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

199
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
199

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Articles linked to this work by shared authors, journal, and citation graph.

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[Improvements in diagnosis and treatment in paediatric and adolescent rheumatology].

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[Rheumatology in Germany in the SARS-CoV-2 pandemic].

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Related Experiment Video

Updated: Nov 12, 2025

Detection of Infectious Virus from Field-collected Mosquitoes by Vero Cell Culture Assay
07:23

Detection of Infectious Virus from Field-collected Mosquitoes by Vero Cell Culture Assay

Published on: June 9, 2011

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[Fever of unknown origin].

Hans-Iko Huppertz1

  • 1Schwachhauser Heerstr. 163a, 28211 Bremen, Deutschland.

Monatsschrift Kinderheilkunde : Organ Der Deutschen Gesellschaft Fur Kinderheilkunde
|March 17, 2021
PubMed
Summary

Fever of unknown origin (FUO) diagnosis requires extensive evaluation for infectious, inflammatory, or malignant causes. Prompt, individualized management is crucial for children facing prolonged fever and diagnostic uncertainty.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Rheumatology

Context:

  • Fever of unknown origin (FUO) presents a diagnostic challenge in pediatrics, often defined by fever lasting 5-10 days.
  • Requires multidisciplinary collaboration including pediatricians, infectious disease specialists, rheumatologists, oncologists, and radiologists.
  • Identifying the underlying cause is critical for appropriate management and to rule out severe conditions.

Purpose:

  • To outline the diagnostic approach and management strategies for FUO in children.
  • To emphasize the importance of a thorough patient history, physical examination, and comprehensive diagnostic workup.
  • To guide clinicians in managing diagnostic uncertainty and parental anxiety.

Summary:

  • Infectious causes are identified in about half of FUO cases; inflammatory, malignant, and non-inflammatory diseases are other potential etiologies.
Keywords:
Body temperatureGlucocorticoidsInfectionInflammationMalignancy

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  • Diagnostic evaluation involves a combination of clinical assessment, laboratory tests, imaging, and histological examinations.
  • Treatment is guided by the underlying cause, with immediate intervention for severe conditions and consideration of glucocorticoids for hyperergic inflammatory states.

    • Impact:

    • Facilitates a structured approach to diagnosing and managing FUO in pediatric patients.
    • Improves clinical decision-making by highlighting key diagnostic tools and potential therapeutic options.
    • Aims to reduce the duration of diagnostic uncertainty and improve outcomes for children with prolonged fever.