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Compromised wound repair caused by perioperative use of ibuprofen
S A Proper1, N A Fenske, S M Burnett
1Department of Internal Medicine, University of South Florida, College of Medicine, Tampa 33612.
Journal of the American Academy of Dermatology
|May 1, 1988
Abstract:
Nonsteroidal anti-inflammatory drugs have been shown to inhibit inflammation, an integral part of the wound-healing process. Compromised wound repair has been demonstrated in laboratory animals administered high-dose nonsteroidal anti-inflammatory drugs, a phenomenon we speculate could occur in humans undergoing surgery. We report a dramatic case of impaired wound healing in a patient ingesting high-dose perioperative ibuprofen, a nonsteroidal anti-inflammatory drug.