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Updated: Nov 12, 2025

Method for Measurement of Viral Fusion Kinetics at the Single Particle Level
Published on: September 7, 2009
Physics of viral dynamics
Robijn F Bruinsma1, Gijs J L Wuite2, Wouter H Roos3
1Department of Physics and Astronomy, University of California, Los Angeles, California, USA.
Abstract:
Viral capsids are often regarded as inert structural units, but in actuality they display fascinating dynamics during different stages of their life cycle. With the advent of single-particle approaches and high-resolution techniques, it is now possible to scrutinize viral dynamics during and after their assembly and during the subsequent development pathway into infectious viruses. In this Review, the focus is on the dynamical properties of viruses, the different physical virology techniques that are being used to study them, and the physical concepts that have been developed to describe viral dynamics.
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