Related Experiment Video
Updated: Nov 12, 2025

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Recent Developments in Devices Used for Gastrointestinal Endoscopy Sedation
Basavana Goudra1, Gowri Gouda2, Preet Mohinder Singh3
1Department of Anesthesiology and Critical Care Medicine, Perelman School of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Propofol sedation during endoscopy can cause hypoxemia, a dangerous drop in oxygen. New nasal cannula devices help prevent this complication by delivering oxygen and positive airway pressure.
Area of Science:
- Medical Devices
- Anesthesiology
- Gastroenterology
Background:
- Hypoxemia is a common and serious risk during gastrointestinal endoscopy.
- Propofol sedation, increasingly used for patient and endoscopist satisfaction, elevates this risk due to potential hypopnea and apnea.
- Complications like coughing and laryngospasm can lead to hypoxemia and cardiac arrest.
Purpose of the Study:
- To review novel nasal cannula devices designed to prevent hypoxemia during gastrointestinal endoscopy.
- To highlight devices that provide apneic oxygenation and continuous positive airway pressure (CPAP).
Main Methods:
- Review of emerging nasal cannula technologies.
- Analysis of device capabilities in oxygen delivery and airway pressure support.
Main Results:
- Standard nasal cannulas are insufficient for positive pressure ventilation during sedation.
- Newer devices offer apneic insufflation and CPAP, reducing the incidence of hypoxemia.
- These devices aim to eliminate dead space and improve oxygenation.
Conclusions:
- Effective prevention of hypoxemia during propofol-sedated endoscopy is crucial.
- Advanced nasal cannula devices represent a significant advancement in patient safety.
- These devices can mitigate risks associated with deep sedation and airway compromise.
More Related Videos
09:36Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
Published on: September 24, 2020
07:22Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing
Published on: December 1, 2023
Related Concept Videos
Endoscopic Procedures I: Esophagogastroduodenoscopy
During an EGD, the endoscope can be used to:
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Stages of General Anesthesia
Endoscopic Procedures II: Colonoscopy
Parenteral Anesthetics: Overview
Skeletal Muscle Relaxants: Therapeutic Uses