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Blood Lead Levels in U.S. Children Ages 1-11 Years, 1976-2016
Kathryn B Egan1, Cheryl R Cornwell1, Joseph G Courtney1
1National Center for Environmental Health, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.
Insights
Blood lead levels (BLLs) in U.S. children have decreased by over 94% in 40 years. However, disparities persist, with higher BLLs linked to race, poverty, and housing age, indicating a need for targeted screening.
Area of Science:
- Environmental health
- Pediatric health
- Public health surveillance
Background:
- Lead exposure significantly impacts child health even at low levels.
- Understanding blood lead level (BLL) distribution is crucial for public health interventions.
- This study examines BLLs in U.S. children over four decades.
Purpose of the Study:
- To describe the distribution of BLLs in U.S. children aged 1-11 years.
- To analyze trends in BLLs over a 40-year period (1976-2016).
- To identify sociodemographic and housing factors associated with BLLs.
Main Methods:
- Utilized data from the National Health and Nutrition Examination Survey (NHANES) II, III, and Continuous NHANES (1976-2016).
- Calculated geometric mean (GM) BLLs and prevalence for children aged 1-11 years.
- Stratified analyses by age group (1-5 and 6-11 years) and sociodemographic/housing characteristics.
Main Results:
- GM BLLs in U.S. children (ages 1-11) decreased by over 94% from 1976-1980 to 2011-2016.
- Despite declines, an estimated 385,775 children had BLLs ≥ 5 µg/dL in 2011-2016.
- Higher GM BLLs were associated with non-Hispanic Black race/ethnicity, lower income-to-poverty ratio, and older housing.
Conclusions:
- Significant population-level reductions in children's BLLs have been achieved over 40 years.
- Persistent disparities in BLLs highlight the need for targeted interventions.
- Risk factors like race, poverty, and housing age can guide blood lead screening efforts.
Background:
Lead can adversely affect child health across a wide range of exposure levels. We describe the distribution of blood lead levels (BLLs) in U.S. children ages 1-11 y by selected sociodemographic and housing characteristics over a 40-y period.
Methods:
Data from the National Health and Nutrition Examination Survey (NHANES) II (1976-1980), NHANES III (Phase 1: 1988-1991 and Phase II: 1991-1994), and Continuous NHANES (1999-2016) were used to describe the distribution of BLLs (in micrograms per deciliter; ) in U.S. children ages 1-11 y from 1976 to 2016. For all children with valid BLLs (), geometric mean (GM) BLLs [95% confidence intervals (CI)] and estimated prevalence (95% CI) were calculated overall and by selected characteristics, stratified by age group (1-5 y and 6-11 y).
Results:
The GM BLL in U.S. children ages 1-5 y declined from (95% CI: 14.3, 16.1) in 1976-1980 to (95% CI: 0.78, 0.88) in 2011-2016, representing a 94.5% decrease over time. For children ages 6-11 y, GM BLL declined from (95% CI: 11.9, 13.4) in 1976-1980 to (95% CI: 0.58, 0.63) in 2011-2016, representing a 95.3% decrease over time. Even so, for the most recent period (2011-2016), estimates indicate that approximately 385,775 children ages 1-11 y had BLLs greater than or equal to the CDC blood lead reference value of . Higher GM BLLs were associated with non-Hispanic Black race/ethnicity, lower family income-to-poverty-ratio, and older housing age.
Discussion:
Overall, BLLs in U.S. children ages 1-11 y have decreased substantially over the past 40 y. Despite these notable declines in population exposures to lead over time, higher GM BLLs are consistently associated with risk factors such as race/ethnicity, poverty, and housing age that can be used to target blood lead screening efforts. https://doi.org/10.1289/EHP7932.
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