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Hemisensory loss in myasthenia gravis
Brandon Marshall1, Umesh Sharma2,3, Lourdes Benes-Lima2,3
1University of Central Florida College of Medicine, Orlando, Florida, USA brmarshall@knights.ucf.edu.
BMJ Case Reports
|March 18, 2021
Summary
This case study presents a unique presentation of myasthenia gravis in an elderly male. The patient experienced atypical symptoms, including hemibody paresthesia, alongside classic signs, challenging typical diagnostic approaches.
Area of Science:
- Neurology
- Clinical Case Studies
Background:
- Myasthenia gravis (MG) is an autoimmune disorder affecting neuromuscular junctions.
- Typical MG symptoms include ptosis, diplopia, dysphagia, and limb weakness, often with ophthalmoplegia.
Observation:
- A 73-year-old man presented with left-sided ptosis, diplopia, and left hemibody paresthesia.
- He also reported intermittent dysphagia and dizziness for one month and diarrhea for two months.
- Notably, ophthalmoplegia was absent.
Findings:
- Serum and electrodiagnostic studies confirmed myasthenia gravis.
- The patient's presentation was non-classic due to the absence of ophthalmoplegia.
- A unique, unexplained hemisensory deficit was observed.
Implications:
- This case underscores the importance of considering atypical presentations of myasthenia gravis.
- It highlights the diagnostic challenges posed by unusual symptom combinations.
- Further research may be needed to understand the mechanisms behind such unique neurological deficits.
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