Related Experiment Video

Updated: Aug 11, 2026

Measurement of the Rheology of Crude Oil in Equilibrium with CO2 at Reservoir Conditions
10:38

Measurement of the Rheology of Crude Oil in Equilibrium with CO2 at Reservoir Conditions

Published on: June 6, 2017

13.0K

Ischaemic stroke as the presenting feature of COVID-19: a series of three cases from Qatar

Yousaf Iqbal1, Peter M Haddad1, Javed Latoo1

  • 1Department of Psychiatry, Hamad Medical Corporation, Doha, Qatar.

Oxford Medical Case Reports
|March 18, 2021
PubMed

Insights

Coronavirus disease (COVID-19) can present as stroke, even without respiratory symptoms. This highlights the need to consider COVID-19 in stroke patients and vice versa.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Vascular Medicine

Background:

  • Coronavirus disease 2019 (COVID-19) is primarily known for causing respiratory illness.
  • Stroke is a recognized but less common complication of COVID-19, often occurring with respiratory symptoms.

Observation:

  • Three patients presented with ischemic stroke as the primary manifestation of COVID-19.
  • Two of these patients experienced no respiratory symptoms during their illness.
  • The affected individuals were relatively young (40-50 years) with varying stroke risk factors.

Findings:

  • COVID-19 infection was confirmed via RT-PCR, and stroke was diagnosed using brain imaging.
  • Two patients exhibited large vessel occlusion and elevated D-dimer levels, indicative of hypercoagulability.
  • Multiple infarcts were observed in two patients, suggesting widespread cerebrovascular impact.

Implications:

  • Clinicians should consider COVID-19 in the differential diagnosis of stroke, particularly in younger patients or those with atypical presentations.
  • Investigating for stroke is crucial in patients diagnosed with COVID-19, even those with mild or absent respiratory symptoms.
  • This underscores the potential for severe neurological complications of COVID-19 beyond the respiratory system.

More Related Videos

Differentiation of Human Pluripotent Stem Cells Into Pancreatic Beta-Cell Precursors in a 2D Culture System10:12

Differentiation of Human Pluripotent Stem Cells Into Pancreatic Beta-Cell Precursors in a 2D Culture System

Published on: December 16, 2021

3.0K
Robust Differentiation of Human iPSCs into a Pure Population of Adipocytes to Study Adipocyte-Associated Disorders10:31

Robust Differentiation of Human iPSCs into a Pure Population of Adipocytes to Study Adipocyte-Associated Disorders

Published on: February 9, 2022

3.8K

Related Concept Videos

Stroke: Introduction and Types01:29

Stroke: Introduction and Types

A stroke is an acute neurological event caused by the sudden disruption of cerebral blood flow, leading to rapid loss of neuronal function. Neurons depend on continuous oxygen and glucose supply, so even brief interruptions can cause irreversible injury within minutes. Strokes are classified into ischemic and hemorrhagic types.Ischemic StrokeIschemic strokes are most common and occur due to arterial occlusion, depriving brain tissue of oxygen and nutrients. This leads to energy failure, ionic...
Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
Transient Ischemic Attack l: Introduction01:26

Transient Ischemic Attack l: Introduction

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...