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COVID-19 and venous thromboembolism: part of a multisystem disease

Daniel Alvarenga Fernandes1, Aline Satomi Yumioka2, Helio Ranes de Menezes Filho3

  • 1Radiology, School of MedicSchool of Medical Sciences. University of Campinas (UNICAMP), Brasil.

Revista Espanola De Enfermedades Digestivas
|March 18, 2021
PubMed

Insights

COVID-19 is associated with an increased risk of acute pancreatitis (AP) and venous thromboembolism (VTE). This highlights the critical need for vigilance regarding thrombotic events in patients with viral infections.

Area of Science:

  • Internal Medicine
  • Infectious Diseases
  • Gastroenterology

Background:

  • The association between viral infections and thrombotic events, including venous thromboembolism (VTE), is increasingly recognized.
  • Recent scientific letters highlight the abdominal manifestations of COVID-19, specifically acute pancreatitis (AP).
  • This observation is supported by a case of AP in a COVID-19 patient who was previously anticoagulated.

Discussion:

  • Viral infections, including human immunodeficiency viruses, hepatitis C, influenza, chikungunya, and Zika, have been linked to VTE.
  • The current COVID-19 pandemic has reinforced the evident association between viral infections and thrombotic complications.
  • Acute pancreatitis in the context of COVID-19 warrants further investigation into its underlying mechanisms and thrombotic potential.

Key Insights:

  • COVID-19 may predispose patients to acute pancreatitis, a condition with a known thrombotic nature.
  • Anticoagulation may be a consideration in managing AP patients with COVID-19, given the thrombotic risk.
  • The broader link between viral infections and VTE underscores the systemic impact of such illnesses.

Outlook:

  • Further research is needed to elucidate the pathophysiological mechanisms connecting COVID-19, AP, and VTE.
  • Clinical vigilance for thrombotic events in patients with COVID-19 and abdominal symptoms is crucial.
  • Understanding these associations can inform clinical management strategies and improve patient outcomes.

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