Related Experiment Video
Updated: Nov 12, 2025
Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
Published on: June 10, 2025
Interarm blood pressure differences and 2-year mortality in acute coronary syndrome patients
Ismail Dogu Kilic1, Hakan Kilci2, Cihan Ilyas Sevgican1
1Department of Cardiology, Pamukkale University, Denizli.
Insights
Interarm blood pressure difference (IABPD) did not significantly predict mortality in acute coronary syndrome (ACS) patients over two years. Further research is needed to clarify the prognostic value of IABPD in this population.
Area of Science:
- Cardiology
- Clinical Medicine
- Public Health
Background:
- Interarm blood pressure difference (IABPD) is a known predictor of cardiovascular mortality.
- Previous studies have indicated a link between IABPD and increased mortality across various patient cohorts.
- The prognostic significance of IABPD in patients with acute coronary syndrome (ACS) requires further investigation.
Purpose of the Study:
- To explore the association between IABPD, measured simultaneously in both arms, and the risk of all-cause mortality.
- To assess the prognostic value of IABPD in patients diagnosed with acute coronary syndrome (ACS).
- To evaluate mortality risk over a 2-year follow-up period in ACS patients with varying degrees of IABPD.
Main Methods:
- Simultaneous blood pressure (BP) measurements were conducted upon initial admission for patients with ACS.
- Systolic IABPD (≥10 mmHg) and diastolic IABPD (≥5 mmHg) were established as cutoff values.
- Kaplan-Meier curves and Cox analysis were employed to evaluate the relationship between IABPD and all-cause mortality.
Main Results:
- The study included 532 patients with ACS, with a mean age of 60.1 years.
- The follow-up duration averaged 23.2 months.
- No significant difference in survival time was observed between patients with systolic IABPD ≥10 mmHg and those with <10 mmHg (P=0.925), nor between diastolic IABPD ≥5 mmHg and <5 mmHg (P=0.251).
Conclusions:
- This study found no significant association between interarm blood pressure difference (IABPD) and all-cause mortality in patients with acute coronary syndrome (ACS) within a 2-year follow-up period.
- The findings suggest that IABPD may not be a strong prognostic indicator for short-term mortality in ACS patients.
- Further research with longer follow-up periods or different methodologies may be necessary to fully elucidate the prognostic importance of IABPD in this specific patient group.
Background And Aims:
Interarm blood pressure difference (IABPD) was associated with increased cardiovascular and all-cause mortality in various cohorts previously. In this study, we planned to explore the association between the IABPD obtained with simultaneous measurements in both arms and the risk of mortality over a 2-year follow-up of patients with acute coronary syndrome (ACS).
Methods:
Simultaneous blood pressure (BP) measurements were performed during initial admission in patients with ACS. Systolic ≥10 mmHg and diastolic ≥5 mmHg absolute IABPD was defined as cutoff values in this study. The relationship of IABPD and all-cause mortality was assessed using Kaplan-Meier curves and Cox analysis.
Results:
A total of 532 patients with ACS were included in the study. Mean age of the study participants was 60.1 ± 12.6. Patients included in the study were followed for 23.2 ± 7.2 months (median 25.3, min: 0, max: 28.7 months). Survival was assessed using Kaplan-Meier curves. Patients with systolic IABPD ≥ 10 mmHg and systolic IABPD < 10 mmHg had an average survival time of 25.94 ± 0.84 and 25.92 ± 0.38 months (P = 0.925), respectively. Survival times of diastolic IABPD ≥5 mmHg and diastolic IABPD <5 mmHg were 26.44 ± 0.62 and 25.71 ± 0.41 (P = 0.251) months, respectively.
Conclusions:
In the current study, we did not find a significant association between IABPD and all-cause mortality in patients with ACS in 2-years follow-up. Future studies may be required for further evaluation of the prognostic importance of IABPD in patients with ACS.
More Related Videos
05:41Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control
Published on: December 16, 2022
10:03Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty
Published on: January 28, 2020
Related Concept Videos
01:10Pre-Procedural Guidelines for Assessing Blood Pressure
01:28Special considerations while measuring blood pressure
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
01:17Measurement of Blood Pressure
01:23Assessment of blood pressure in brachial artery(two-step method)
01:30Acute Coronary Syndrome III: Diagnostic Studies
01:25Errors occurring during blood pressure monitoring
Several factors...