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Related Experiment Video

Updated: Nov 12, 2025

An In Vivo Murine Sciatic Nerve Model of Perineural Invasion
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[Intra-oral Perineurioma, a case report].

A Yousif, A C Dutman, J M van Ingen

    Nederlands Tijdschrift Voor Tandheelkunde
    |March 18, 2021
    PubMed
    Summary
    This summary is machine-generated.

    A rare soft tissue perineurioma tumor was found in a 48-year-old woman's cheek. This slow-growing, asymptomatic mass was successfully removed via excisional biopsy.

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    Area of Science:

    • Oral and Maxillofacial Surgery
    • Surgical Pathology
    • Oncology

    Background:

    • Perineuromas are rare, benign nerve sheath tumors.
    • Intra-oral presentations are exceptionally uncommon, posing diagnostic challenges.
    • Slow-growing, asymptomatic masses require careful evaluation.

    Observation:

    • A 48-year-old female presented with a 3-year history of a slow-growing, asymptomatic intra-oral mass.
    • A 5 cm well-defined tumor was located in the right cheek, with intact overlying mucosa and skin.
    • Magnetic Resonance Imaging (MRI) suggested a solitary mass with benign features.

    Findings:

    • Histopathological examination confirmed a soft tissue perineurioma.
    • The tumor exhibited benign characteristics on imaging and pathology.
    • Surgical excision was the chosen treatment modality.

    Implications:

    • This case highlights the importance of considering rare soft tissue tumors in the differential diagnosis of intra-oral masses.
    • Accurate histopathological diagnosis is crucial for appropriate management of perineuromas.
    • Early detection and surgical management can lead to favorable outcomes for benign intra-oral tumors.